Now showing items 765-784 of 976

    • Role of mitochondria in neuronal apoptosis 

      Gorman, Adrienne M.; Ceccatelli, Sandra; Orrenius, Sten (Karger Publishers, 2000-12)
      Apoptosis is a controlled form of cell death that participates in the demise of neuronal cells during development, neurodegenerative disorders and exposure to neurotoxic agents. In recent years, the mitochondria have emerged ...
    • Rotational Modulation of M/L Dwarfs due to Magnetic Spots 

      Butler, Ray (2007)
      We find periodic I-band variability in two ultracool dwarfs, TVLM 513-46546 and 2MASS J00361617+1821104, on either side of the M/L dwarf boundary. Both of these targets are short-period radio transients, with the detected ...
    • A route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin derivatives with quaternary centers adjacent to the ring nitrogen from Methyl α-d-Mannopyranoside 

      Chadda, Rekha; Murphy, Paul V. (Wiley, 2020-02-03)
      6-Alkylated-8-azido-1,6-octadiene derivatives were prepared from methyl α-D-mannopyranoside. The sequence to allylic azide precursors included a Horner-Wadsworth-Emmons reaction with a concomitant epimerization that ...
    • Ruthenium-centred btp glycoclusters as inhibitors for Pseudomonas aeruginosa biofilm formation 

      O'Reilly, Ciaran; Blasco, Salvador; Parekh, Bina; Collins, Helen; Cooke, Gordon; Gunnlaugsson, Thorfinnur; Byrne, Joseph P. (Royal Society of Chemistry, 2021-05-04)
      Carbohydrate-decorated clusters (glycoclusters) centred on a Ru(II) ion were synthesised and tested for their activity against Pseudomonas aeruginosa biofilm formation. These clusters were designed by conjugating a range ...
    • Salts, binary and ternary cocrystals of pyrimethamine: mechanosynthesis, solution crystallization and crystallization from the gas phase 

      O’Malley, Ciaran; Bouchet, Chloe; Manyara, Grayce; Walsh, Niamh; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2020-11-24)
      A series of salts and binary and ternary cocrystals of the antimalaria drug pyrimethamine (PYR) are reported. PYR has a donor–acceptor–donor (DAD) and a donor–acceptor (DA) binding site, and cocrystallization experiments ...
    • Scalar evolution equations for shear waves in incompressible solids: a simple derivation of the Z, ZK, KZK and KP equations 

      Destrade, Michel (The Royal Society, 2011-07-08)
      We study the propagation of two-dimensional finite-amplitude shear waves in a nonlinear pre-strained incompressible solid, and derive several asymptotic amplitude equations in a simple, consistent and rigorous manner. The ...
    • Scaling behavior of polymers at liquid/liquid interfaces 

      Cheung, David L. (American Chemical Society, 2015-09-14)
      The dynamics of a polymer chain confined in a soft 2D slit formed by two immiscible liquids is studied by means of molecular dynamics simulations. We show that the scaling behavior of a polymer confined between two liquids ...
    • Sea-spray regulates sulfate cloud droplet activation over oceans 

      Fossum, Kirsten N.; Ovadnevaite, Jurgita; Ceburnis, Darius; Preißler, Jana; Snider, Jefferson R.; Huang, Ru-Jin; Zuend, Andreas; O’Dowd, Colin (Nature Research (part of Springer Nature), 2020-04-08)
      Sulfate aerosols are typically the dominant source of cloud condensation nuclei (CCN) over remote oceans and their abundance is thought to be the dominating factor in determining oceanic cloud brightness. Their activation ...
    • A search for brief optical flashes associated with the SETI target KIC 8462852 

      Gillanders, Gary; Lang, Mark (IOP Publishing, 2016-02-18)
      The F-type star KIC. 8462852 has recently been identified as an exceptional target for search for extraterrestrial intelligence (SETI) observations. We describe an analysis methodology for optical SETI, which we have used ...
    • A search for CO+ in planetary nebulae 

      Redman, Matt P. (2007)
      We have carried out a systematic search for the molecular ion CO+ in a sample of 8 protoplanetary and planetary nebulae in order to determine the origin of the unexpectedly strong HCO+ emission previously detected in these ...
    • A Search for Dark Matter Annihilation with the Whipple 10m Telescope 

      Lang, Mark (2008)
      We present observations of the dwarf galaxies Draco and Ursa Minor, the local group galaxies M32 and M33, and the globular cluster M15 conducted with the Whipple 10m gamma-ray telescope to search for the gamma-ray signature ...
    • A search for optical bursts from RRAT J1819-1458: II. Simultaneous ULTRACAM-Lovell Telescope observations 

      Shearer, Andrew (2011)
      The Rotating RAdio Transient (RRAT) J1819-1458 exhibits ~3 ms bursts in the radio every ~3 min, implying that it is visible for only ~1 per day. Assuming that the optical light behaves in a similar manner, long exposures ...
    • A search for pulsations from Geminga above 100 GeV with VERITAS 

      Connolly, M.P.; Gillanders, Gary; Moriarty, P.; Lang, Mark (American Astronomical Society, 2015-02-10)
      We present the results of 71.6 hr of observations of the Geminga pulsar (PSR J0633+1746) with the VERITAS very-high-energy gamma-ray telescope array. Data taken with VERITAS between 2007 November and 2013 February were ...
    • A Search for Pulsed TeV Gamma Ray Emission from the Crab Pulsar 

      Lang, Mark; Gillanders, Gary (1999)
      We present the results of a search for pulsed TeV emission from the Crab pulsar using the Whipple Observatory's 10m gamma-ray telescope. The direction of the Crab pulsar was observed for a total of 73.4 hours between 1994 ...
    • A Search for Pulsed TeV Gamma Ray Emission from the Crab Pulsar 

      Lang, Mark; Gillanders, Gary; Burdett, A. M.; Bond, I. H.; Boyle, P. J.; Bradbury, S. M.; Buckley, J. H.; Carter-Lewis, D. A.; Catanese, M.; Cawley, M. F.; D'Vali, M.; Fegan, D. J.; Fegan, S. J.; Finley, J. P.; Gaidos, J. A.; Gillanders, G. H.; Hall, T. A.; Hillas, A. M.; Kildea, J.; Knapp, J.; Krennrich, F.; Lang, M. J.; LeBohec, S.; Lessard, R. W.; Masterson, C.; Moriarty, P.; Quinn, J.; Rose, H. J.; Samuelson, F. W.; Sembroski, G. H.; Srinivasan, R.; Vassiliev, V. V.; Weekes, T. C. (1999)
      We present the results of a search for pulsed TeV emission from the Crab pulsar using the Whipple Observatory's 10m gamma-ray telescope. The direction of the Crab pulsar was observed for a total of 73.4 hours between 1994 ...
    • Search for Pulsed TeV Gamma-ray Emission from the Crab Pulsar 

      Lang, Mark; Gillanders, Gary (1999)
      We present the results of a search for pulsed TeV emission from the Crab pulsar using the Whipple Observatory's 10 m gamma-ray telescope. The direction of the Crab pulsar was observed for a total of 73.4 hours between 1994 ...
    • Search for Pulsed TeV Gamma-ray Emission from the Crab Pulsar 

      Lang, Mark; Gillanders, Gary; Lessard, R. W.; Bond, I. H.; Bradbury, S. M.; Buckley, J. H.; Burdett, A. M.; Carter-Lewis, D. A.; Catanese, M.; Cawley, M. F.; D'Vali, M.; Fegan, D. J.; Finley, J. P.; Gaidos, J. A.; Gillanders, G. H.; Hall, T.; Hillas, A. M.; Krennrich, F.; Lang, M. J.; Masterson, C.; Moriarty, P.; Quinn, J.; Rose, H. J.; Samuelson, F. W.; Sembroski, G. H.; Srinivasan, R.; Vassiliev, V. V.; Weekes, T. C. (1999)
      We present the results of a search for pulsed TeV emission from the Crab pulsar using the Whipple Observatory's 10 m gamma-ray telescope. The direction of the Crab pulsar was observed for a total of 73.4 hours between 1994 ...
    • Seismic Rayleigh waves on an exponentially graded, orthotropic half-space 

      Destrade, Michel (The Royal Society, 2007)
      Efforts at modelling the propagation of seismic waves in half-spaces with continuously varying properties have mostly been focused on shear-horizontal waves. Here, a sagittally polarized (Rayleigh type) wave travels along ...
    • Selection shapes synonymous stop codon use in mammals 

      Seoighe, Cathal; Kiniry, Stephen J.; Peters, Andrew; Baranov, Pavel V.; Yang, Haixuan (Springer (part of Springer Nature), 2020-07-02)
      Phylogenetic models of the evolution of protein-coding sequences can provide insights into the selection pressures that have shaped them. In the application of these models synonymous nucleotide substitutions, which do not ...