Now showing items 523-542 of 976

    • Mechanical characterization of brain tissue in simple shear at dynamic strain rates 

      Rashid, Badar; Destrade, Michel; Gilchrist, Michael D. (Elsevier, 2013-12)
      During severe impact conditions, brain tissue experiences a rapid and complex deformation, which can be seen as a mixture of compression, tension and shear. Diffuse axonal injury (DAI) occurs in animals and humans when ...
    • Mechanical characterization of brain tissue in tension at dynamic strain rates 

      Rashid, B,Destrade, M,Gilchrist, MD; Destrade, Michel; Gilchrist, Michael D. (Elsevier, 2012-09-10)
      Mechanical characterization of brain tissue at high loading velocities is crucial for modeling Traumatic Brain Injury (TBI). During severe impact conditions, brain tissue experiences compression, tension and shear. Limited ...
    • Mechanical instability tuning of a magnetorheological elastomer composite laminate 

      Chen, Vincent W.; Arora, Nitesh; Goshkoderia, Artemii; Willey, Carson L.; Turgut, Zafer; Buskohl, Philip R.; Rudykh, Stephan; Juhl, Abigail T. (Elsevier, 2022-12-28)
      Magnetorheological elastomers (MRE) can change their shape and properties when activated by an external magnetic field. The attractive tunable properties of this stimuli-responsive composite can be further amplified by ...
    • Mechanical properties of excised human skin 

      Ni Annaidh, Aisling; Ottenio, M.; Bruyere, K.; Destrade, Michel; Gilchrist, Michael D. (Springer Verlag, 2010)
      In this study we have investigated in influence of location, gender and orientation on the deformation characteristics of 55 samples of human excised skin. Uniaxial tensile tests were carried out at a strain rate of ...
    • Mechanics of human brain organoids 

      Balbi, Valentina; Destrade, Michel; Goriely, Alain (American Physical Society, 2020-01-02)
      Organoids are prototypes of human organs derived from cultured human stem cells. They provide a reliable and accurate experimental model to study the physical mechanisms underlying the early developmental stages of human ...
    • Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization 

      Gupta, Sanjeev; Cuffe, Lorraine; Szegezdi, Eva; Logue, Susan E.; Neary, Catherine; Healy, Sandra; Samali, Afshin (2010)
      During apoptosis, the process of mitochondrial outer membrane permeabilization (MOMP) represents a point-of-no-return as it commits the cell to death. Here we have assessed the role of caspases, Bcl-2 family members and ...
    • Mechanochemical tuning of the binaphthyl conformation at the air water interface 

      Cheung, David L. (Wiley, 2015-06-12)
      Gradual and reversible tuning of the torsion angle of an amphiphilic chiral binaphthyl, from −90° to −80°, was achieved by application of a mechanical force to its molecular monolayer at the air–water interface. This 2D ...
    • Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context 

      André, Sabine; Kaltner, Herbert; Kayser, Klaus; Murphy, Paul V.; Gabius, Hans-Joachim (Springer, 2015-11-09)
      Recognition of glycans by lectins leads to cell adhesion and growth regulation. The specificity and selectivity of this process are determined by carbohydrate structure (sequence and shape) and topology of its presentation. ...
    • Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy 

      Pettenuzzo, Andrea; Pigot, Rebecca; Ronconi, Luca (De Gruyter Open, 2016-04-07)
      Glucose is a key source of energy and an essential nutrient for cell growth. Rapidly dividing cancer cells are well-known to require more nutrients and energy than normal ones to sustain their higher proliferation ...
    • Metallacarboranes and their interactions: theoretical insights and their applicability 

      Farràs, Pau; Juárez-Pérez, Emilio J.; Lepšík, Martin; Luque, Rafael; Núñez, Rosario; Teixidor, Francesc (Royal Society of Chemistry, 2012-02-14)
      This tutorial review will deal with the study of metallacarboranes and their interactions with other molecules from a theoretical point of view. This contribution is devoted to guide experimental chemists through calculations ...
    • Metallacarboranes as building blocks for polyanionic polyarmed aryl-ether materials 

      Farràs, Pau; Teixidor, Francesc; Kivekäs, Raikko; Sillanpää, Reijo; Viñas, Clara; Grüner, Bohumir; Cisarova, Ivana (American Chemical Society, 2008-09-20)
      Polyanionic species have been obtained in high yield by a new route in the ring-opening reaction of cyclic oxonium [3,3′-Co(8-C4H8O2-1,2-C2B9H10)(1′,2′-C2B9H11)] (2) by using carboxylic acids, Grignard reagents, and ...
    • Methodical fitting for mathematical models of rubber-like materials 

      Destrade, Michel; Saccomandi, Giuseppe; Sgura, Ivonne (The Royal Society Publishing, 2017-02-08)
      A great variety of models can describe the nonlinear response of rubber to uniaxial tension. Yet an in-depth understanding of the successive stages of large extension is still lacking. We show that the response can be ...
    • Methods and techniques employed to monitor and manage carbon capture and sequestration (CCS) induced seismicity 

      McNamara, David D. (GNS Science, 2016)
      This report discusses the topic of induced seismicity resulting from the operations of subsurface CO2 injection at Carbon Capture and Storage (CCS) sites. The potential for induced seismicity to occur in CCS projects is ...
    • Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response 

      Samali, Afshin; FitzGerald, Una; Deegan, Shane; Gupta, Sanjeev (2010)
      The endoplasmic reticulum (ER) is the site of folding of membrane and secreted proteins in the cell. Physiological or pathological processes that disturb protein folding in the endoplasmic reticulum cause ER stress and ...
    • Methyl 2,3,6-tri-O-Benzoyl-4-O-(tert-butyldimethylsilyl)-β-d-galactopyranoside 

      Bennett, Jack; Roux, Amélie; Murphy, Paul V. (MDPI (Multidisciplinary Digital Publishing Institute), 2017-03-19)
      Methyl 2,3,6-tri-O-benzoyl-4-O-(tert-butyldimethylsilyl)-β-d-galactopyranoside was synthesized in 47% yield by the silylation of a partially benzoylated galactose derivative, prepared from methyl β-d-galactopyranoside. ...
    • Microbial electrochemical technologies: Electronic circuitry and characterization tools 

      Sánchez, Carlos; Dessì, Paolo; Duffy, Maeve; Lens, Piet N.L. (Elsevier, 2019-11-16)
      Microbial electrochemistry merges microbiology, electrochemistry and electronics to provide a set of technologies for environmental engineering applications. Understanding the electronic concepts is crucial for effectively ...
    • Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions 

      Dessì, Paolo; Rovira-Alsina, Laura; Sánchez, Carlos; Dinesh, G. Kumaravel; Tong, Wenming; Chatterjee, Pritha; edesco, MicheleT; Farràs, Pau; Hamelers, Hubertus M.V.; Puig, Sebastià (Elsevier, 2020-12-01)
      Decarbonisation of the economy has become a priority at the global level, and the resulting legislative pressure is pushing the chemical and energy industries away from fossil fuels. Microbial electrosynthesis (MES) has ...
    • Microcavity array supported lipid bilayer models of ganglioside – influenza hemagglutinin1 binding 

      Berselli, Guilherme B.; Sarangi, Nirod Kumar; Gimenez, Aurélien V.; Murphy, Paul V.; Keyes, Tia E. (Royal Society of Chemistry, 2020-08-07)
      The binding of influenza receptor (HA(1)) to membranes containing different glycosphingolipid receptors was investigated at Microcavity Supported Lipid Bilayers (MSLBs). We observed that HA(1)preferentially binds to GD1a ...
    • Microcirculation imaging based on full-range high-speed spectral domain correlation mapping optical coherence tomography 

      Subhash, Hrebesh M.; Leahy, Martin (SPIE (International Society for Optics and Photonics, 2014)
      Microcirculation imaging is a key parameter for studying the pathophysiological processes of various disease conditions, in both clinical and fundamental research. A full-range spectral-domain correlation mapping optical ...
    • Microplastics in corals: An emergent threat 

      de Oliveira Soares, Marcelo; Matos, Eliana; Lucas, Caroline; Rizzo, Lucia; Allcock, A. Louise; Rossi, Sergio (Elsevier, 2020-11-01)
      This article seeks to present a summary of knowledge and thus improve awareness of microplastic impacts on corals. Recent research suggests that microplastics have a variety of species-specific impacts. Among them, a reduced ...