Browsing College of Science by Title
Now showing items 513-532 of 976
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Manipulating cocrystal size and morphology using a combination of temperature cycling and additives
(American Chemical Society, 2020-11-20)A cooling crystallization of benzoic acid and isonicotinamide in ethanol yields the 1:1 cocrystal with an extreme needle-like morphology with an initial mean aspect ratio of ∼10 and a size of ∼64 μm. We demonstrate that ... -
Manipulation of intestinal epithelial cell function by the cell contact-dependent type III secretion systems of Vibrio parahaemolyticus
(Frontiers Media, 2014-01-10)Vibrio parahaemolyticus elicits gastroenteritis by deploying Type III Secretion Systems (TTSS) to deliver effector proteins into epithelial cells of the human intestinal tract. The bacteria must adhere to the human cells ... -
Mapping the terrain for the Lean Supply Chain 4.0
(Emerald, 2023-10-03)This study aims to carry out a systematic literature review (SLR) on the integration of Lean, Industry 4.0 and the supply chain or the Lean Supply Chain (LSC) 4.0. The research analyses the current research on the LSC 4.0 ... -
A mathematical model for the release of peptide-binding drugs from affinity hydrogels
(Palgrave, 2015-01-09)A mathematical model for the release of peptide-binding drugs from affinity hydrogels is analyzed in detail. The model is not specific to any particular peptide/drug/gel system, and can describe drug release from a large ... -
A Maximal Eigenvalue Method for Detecting Process Representative Genes by Integrating Data from Multiple Sources
(2008)An important problem in computational biology is the identification of candidate genes which can be considered as representative of the different cellular processes taking place in the cell as it evolves through time. ... -
Measuring knife stab penetration into skin simulant using a novel biaxial tension device
(Elsevier, 2008)This paper describes the development and use of a biaxial measurement device to analyse the mechanics of knife stabbings. In medicolegal situations it is typical to describe the consequences of a stabbing incident in ... -
Measuring the linear and nonlinear elastic properties of brain tissue with shear waves and inverse analysis
(Springer, 2015-02-20)We use supersonic shear wave imaging (SSI) technique to measure not only the linear but also the nonlinear elastic properties of brain matter. Here, we tested six porcine brains ex vivo and measured the velocities of the ... -
Measuring the micro-polarity and hydrogen-bond donor/acceptor ability of thermoresponsive N-isopropylacrylamide/N-tert-butylacrylamide copolymer films using solvatochromic indicators
(application/pdf, 2009)Thin polymer films are important in many areas of biomaterials research, biomedical devices, and biological sensors. The accurate in situ measurement of multiple physicochemical properties of thin polymer films is critical ... -
Measuring the Micro-Polarity and Hydrogen-Bond Donor/Acceptor Ability of Thermoresponsive N-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Films Using Solvatochromic Indicators
(2009)Thin polymer films are important in many areas of biomaterials research, biomedical devices, and biological sensors. The accurate in situ measurement of multiple physicochemical properties of thin polymer films is critical ... -
Mechanical characterization of brain tissue in compression at dynamic strain rates
(Elsevier, 2012-03-02)Traumatic brain injury (TBI) occurs when local mechanical load exceeds certain tolerance levels for brain tissue. Extensive research has been done previously for brain matter experiencing compression at quasistatic loading; ... -
Mechanical characterization of brain tissue in simple shear at dynamic strain rates
(Elsevier, 2013-12)During severe impact conditions, brain tissue experiences a rapid and complex deformation, which can be seen as a mixture of compression, tension and shear. Diffuse axonal injury (DAI) occurs in animals and humans when ... -
Mechanical characterization of brain tissue in tension at dynamic strain rates
(Elsevier, 2012-09-10)Mechanical characterization of brain tissue at high loading velocities is crucial for modeling Traumatic Brain Injury (TBI). During severe impact conditions, brain tissue experiences compression, tension and shear. Limited ... -
Mechanical instability tuning of a magnetorheological elastomer composite laminate
(Elsevier, 2022-12-28)Magnetorheological elastomers (MRE) can change their shape and properties when activated by an external magnetic field. The attractive tunable properties of this stimuli-responsive composite can be further amplified by ... -
Mechanical properties of excised human skin
(Springer Verlag, 2010)In this study we have investigated in influence of location, gender and orientation on the deformation characteristics of 55 samples of human excised skin. Uniaxial tensile tests were carried out at a strain rate of ... -
Mechanics of human brain organoids
(American Physical Society, 2020-01-02)Organoids are prototypes of human organs derived from cultured human stem cells. They provide a reliable and accurate experimental model to study the physical mechanisms underlying the early developmental stages of human ... -
Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization
(2010)During apoptosis, the process of mitochondrial outer membrane permeabilization (MOMP) represents a point-of-no-return as it commits the cell to death. Here we have assessed the role of caspases, Bcl-2 family members and ... -
Mechanochemical tuning of the binaphthyl conformation at the air water interface
(Wiley, 2015-06-12)Gradual and reversible tuning of the torsion angle of an amphiphilic chiral binaphthyl, from −90° to −80°, was achieved by application of a mechanical force to its molecular monolayer at the air–water interface. This 2D ... -
Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context
(Springer, 2015-11-09)Recognition of glycans by lectins leads to cell adhesion and growth regulation. The specificity and selectivity of this process are determined by carbohydrate structure (sequence and shape) and topology of its presentation. ... -
Metal-based glycoconjugates and their potential in targeted anticancer chemotherapy
(De Gruyter Open, 2016-04-07)Glucose is a key source of energy and an essential nutrient for cell growth. Rapidly dividing cancer cells are well-known to require more nutrients and energy than normal ones to sustain their higher proliferation ... -
Metallacarboranes and their interactions: theoretical insights and their applicability
(Royal Society of Chemistry, 2012-02-14)This tutorial review will deal with the study of metallacarboranes and their interactions with other molecules from a theoretical point of view. This contribution is devoted to guide experimental chemists through calculations ...