Now showing items 27-46 of 566

  • Bcl-2 family on guard at the ER 

    Samali, Afshin; Sanjeev, Gupta; Ní Chonghaile, Tríona; MacDonald, David C; Szegezdi, Eva (American Physiological Society, 2009)
    The endoplasmic reticulum (ER) is the main site for protein folding, lipid biosynthesis and calcium storage in the cell. Disturbances of these critical cellular functions lead to ER stress. The ER responds to disturbances ...
  • Bending instabilities of soft biological tissues 

    Destrade, Michel; Ní Annaidh, Aisling (Elsevier, 2009-12-15)
    Rubber components and soft biological tissues are often subjected to large bending deformations while 'in service'. The circumferential line elements on the inner face of a bent block can contract up to a certain critical ...
  • Beyond the green: understanding the evolutionary puzzle of plant and algal cell walls 

    Popper, Zoë A.; Tuohy, Maria G. (American Society of Plant Biologists, 2010-04-26)
    Niklas (2000) defined plants as “photosynthetic eukaryotes,” thereby including brown, red, and green macroalgae and microalgae. These groups share several features, including the presence of a complex, dynamic, and ...
  • Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins 

    Sabine André, Sabine; O'Sullivan, Shane; Koller, Christiane; Murphy, Paul V.; Gabius, Hans-Joachim (Royal Society of Chemistry, 2015-02-17)
    Emerging insights into the functional spectrum of tissue lectins leads to identification of new targets for the custom-made design of potent inhibitors, providing a challenge for synthetic chemistry. The affinity and ...
  • Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity. 

    Wang, Guan-Nan; Murphy, Paul V. (Royal Society of Chemistry, 2012-06-29)
    The emerging functional versatility of cellular glycans makes research on the design of synthetic inhibitors a timely topic. In detail, the combination of ligand (or headgroup or contact site) structure with spatial ...
  • Bimodular rubber buckles early in bending 

    Destrade, Michel; Gilchrist, Michael D.; Motherway, Julie A. (Elsevier, 2009-12-03)
    A block of rubber eventually buckles under severe flexure, and several axial wrinkles appear on the inner curved face of the bent block. Experimental measurements reveal that the buckling occurs earlier - at lower compressive ...
  • Bioassay models with natural mortality and random effects 

    Hinde, John (2011)
    In fitting dose-response models to entomological data it is often necessary to take account of natural mortality and/or overdispersion. The standard approach to handle natural mortality is to use Abbott¿s formula. Standard ...
  • Bioassays with natural mortality: handling overdispersion using random effects 

    Hinde, John (2011)
    In fitting dose-response models to entomological data it is often necessary to take account of natural mortality and/or overdispersion. The standard approach to handle natural mortality is to use Abbott's formula (Abbott, ...
  • Bioinformatic identification and analysis of extensins in the plant kingdom 

    Liu, Xiao; Wolfe, Richard; Welch, Lonnie R.; Domozych, David S.; Popper, Zoë A.; Showalter, Allan M. (Public Library of Science, 2016-02-26)
    Extensins (EXTs) are a family of plant cell wall hydroxyproline-rich glycoproteins (HRGPs) that are implicated to play important roles in plant growth, development, and defense. Structurally, EXTs are characterized by the ...
  • Bleustein-Gulyaev waves in some functionally graded materials 

    Destrade, Michel (Elsevier, 2006-02-28)
    Functionally Graded Materials are inhomogeneous elastic bodies whose properties vary continuously with space. Hence consider a half-space (x2>0) occupied by a special Functionally Graded Material made of an hexagonal (6 ...
  • Bodipy-ruthenium(II) tris-bipyridyl dyads for homogeneous photochemical oxidations 

    Farràs, Pau; Benniston, Andrew C. (Elsevier, 2014-10-28)
    Two Bodipy-ruthenium(II) tris-bipyridyl dyads were synthesized for use as sensitizers in photochemical oxidation reactions of organic substrates. The synthetic strategy involved the use of a simple ‘click’ CuAAC reaction ...
  • Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses 

    Boyd, Aoife (American Society for Microbiology, 2008-01)
    Certain bacteria use a type III secretion system (TTSS) to deliver effector proteins that interfere with cell function into host cells. While transcription of genes encoding TTSS components has been demonstrated, studies ...
  • The bosonic vertex operator algebra on a genus g Riemann surface 

    Tuite, Michael P.; Zuevsky, Alexander (2011-08)
    We discuss the partition function for the Heisenberg vertex operator algebra on a genus g Riemann surface formed by sewing handles to a Riemann sphere. In particular, it is shown how the partition can be computed by means ...
  • Bumblebee learning and memory is impaired by chronic exposure to a neonicotinoid pesticide. 

    Stanley, Dara A.; Smith, Karen E.; Raine, Nigel E. (Nature Publishing Group, 2015-11-16)
    Bumblebees are exposed to pesticides applied for crop protection while foraging on treated plants, with increasing evidence suggesting that this sublethal exposure has implications for pollinator declines. The challenges ...
  • Catastrophic thinning of dielectric elastomers 

    Zurlo, G.; Destrade, Michel; DeTommasi, M.; Puglisi, G. (American Physical Society, 2017-02-15)
    We provide an energetic insight into the catastrophic nature of thinning instability in soft electroactive elastomers. This phenomenon is a major obstacle to the development of giant actuators, yet it is neither completely ...
  • Cell complexes database for the Bianchi groups 

    Rahm, Alexander D. (NUI Galway, 2016-05-18)
    This is a database of quotients by Bianchi groups of two-dimensional cellular equivariant retracts of Hyperbolic three-space. The Bianchi groups SL(2, A), with A the ring of integers in the imaginary quadratic number field ...
  • Cell cycle-dependent mobility of Cdc45 in living cells determined by fluorescence correlation spectroscopy. 

    Broderick, Ronan; Ramadurai, Sivaramakrishnan; Togashi, Denisio M.; Ryder, Alan G.; Langowski, Jorg (Public Library of Science, 2012)
    Eukaryotic DNA replication is a dynamic process requiring the co-operation of specific replication proteins. We measured the mobility of eGFP-Cdc45 by Fluorescence Correlation Spectroscopy (FCS) in vivo in asynchronous ...
  • Cell wall evolution and diversity 

    Fangel, Jonatan U.; Ulvskov, Peter; Knox, J. P.; Mikkelsen, Maria Dalgaard; Harholt, Jesper; Popper, Zoë A.; Willats, William G. T. (Frontiers Media, 2012-07-06)
    Plant cell walls display a considerable degree of diversity in their compositions and molecular architectures. In some cases the functional significance of a particular cell wall type appears to be easy to discern: secondary ...
  • The cell walls of pteridophytes and other green plants - a review 

    Popper, Zoë A. (British Pteridological Society, 2006-12-22)
    The cell wall is one of the defining characteristics of plants and is a fundamental component in normal growth and development. Cell wall composition is a potentially valuable source of phylogenetic information as notable ...
  • A census of human soluble protein complexes 

    Yang, Haixuan (Elsevier, 2012-08-11)
    Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative ...