Browsing College of Science by Author "http://dx.doi.org/10.13039/501100001590"
Now showing items 1-5 of 5
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Examination of oestrus-dependent alterations of bovine cervico-vaginal mucus glycosylation for potential as optimum fertilisation indicators
Le Berre, Marie; Gerlach, Jared Q.; Loughrey, Catherine; Creavin, Aileen; Pluta, Katarzyna; Gallagher, Mary; Carrington, Stephen D.; Joshi, Lokesh; Kilcoyne, Michelle (Royal Society of Chemistry, 2021-03-09)Oestrus is the period in the sexual cycle of female mammals during which ovulation occurs, where they become most receptive to mating and are most fertile. Efficient detection of oestrus is a key component in successful ... -
Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders
Kenny, Elaine M.; Cormican, Paul; Furlong, Sarah; Heron, Eleisa; Kenny, Graham; Fahey, Ciara; Kelleher, Eric; Ennis, Sean; Tropea, Daniela; Anney, Richard; Corvin, Aiden P.; Donohoe, Gary; Gallagher, Louise; Gill, Michael; Morris, Derek W. (Springer Nature, 2013-10-15)Schizophrenia (SZ) and autism spectrum disorders (ASDs) are complex neurodevelopmental disorders that may share an underlying pathology suggested by shared genetic risk variants. We sequenced the exonic regions of 215 genes ... -
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells
Jaafar, Rola; Mnich, Katarzyna; Dolan, Sarah; Hillis, Jennifer; Almanza, Aitor; Logue, Susan E.; Samali, Afshin; Gorman, Adrienne M. (Elsevier, 2018-02-06)Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ... -
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster
Mills, Wilbur Kyle; Lee, Yuh Chwen G.; Kochendoerfer, Antje M.; Dunleavy, Elaine M.; Karpen, Gary H. (eLife Sciences Publications, 2019-11-05)Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that ... -
Stress management at the ER: regulators of ER stress-induced apoptosis.
Gorman, Adrienne M.; Healy, Sandra J.M.; Jäger, Richard; Samali, Afshin (Elsevier, 2012-02-17)The endoplasmic reticulum (ER) is an elaborate cellular organelle essential for cell function and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins which are ...