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dc.contributor.authorAbu-Rub, Mohammaden
dc.contributor.authorMcMahon, Siobhanen
dc.contributor.authorZeugolis, Dimitrios I.en
dc.contributor.authorPandit, Abhayen
dc.date.accessioned2010-10-14T09:15:39Zen
dc.date.available2010-10-14T09:15:39Zen
dc.date.issued2010-06en
dc.identifier.citationAbu-Rub, M., McMahon, S., Zeugolis, D. I., Windebank, A., & Pandit, A. Spinal cord injury in vitro: modelling axon growth inhibition. Drug Discovery Today, 15(11-12), 436-443.en
dc.identifier.issn1359-6446en
dc.identifier.urihttp://hdl.handle.net/10379/1336en
dc.description.abstractOver the past three decades, tremendous progress has been made in elucidating mechanisms underlying regenerative failure after spinal cord injury and in devising therapeutic approaches to promote functional nerve regeneration. Various in vitro assays have been developed using brain and/or spinal cord neuronal cells to study axon growth in conditions that represent the post-injury environment. This review outlines the current models used to dissect, analyze and manipulate specific aspects of spinal cord injury leading to axon growth inhibition.en
dc.formatapplication/pdfen
dc.publisherElsevieren
dc.subjectSpinal cord injuryen
dc.subjectRegenerative failureen
dc.subjectNetwork of Excellence for Functional Biomaterialsen
dc.titleSpinal cord injury in vitro: Modelling axon growth inhibitionen
dc.typeArticleen
dc.description.peer-reviewedpeer-revieweden
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