Browsing Surgery (Scholarly Articles) by Subject "Breast cancer susceptibility"
Now showing items 1-3 of 3
-
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
(Wiley, 2012-07)A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these ... -
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
(Nature Publishing Group (Macmillan), 2013-03-27)Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We ... -
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
(Nature Publishing Group (Macmillan), 2013-04)TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ~480 SNPs at the TERT locus in breast (n = 103,991), ...