Browsing School of Chemistry (Scholarly Articles) by Subject "Glycosylation"
Now showing items 1-3 of 3
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Lectins: getting familiar with translators of the sugar code
(MDPI, 2015-01-22)The view on the significance of the presence of glycans in glycoconjugates is undergoing a paradigmatic change. Initially mostly considered to be rather inert and passive, the concept of the sugar code identifies glycans ... -
Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context
(Springer, 2015-11-09)Recognition of glycans by lectins leads to cell adhesion and growth regulation. The specificity and selectivity of this process are determined by carbohydrate structure (sequence and shape) and topology of its presentation. ... -
Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design
(Springer, 2016-06-24)A hallmark of endogenous lectins is their ability to select a few distinct glycoconjugates as counterreceptors for functional pairing from the natural abundance of cellular glycoproteins and glycolipids. As a consequence, ...