Browsing School of Chemistry by Author "Nobis, Max"
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Synthesis of migrastatin and its macroketone analogue and in vivo FRAP analysis of the macroketone on E-Cadherin dynamics
Lo Re, Daniele; Zhou, Ying; Nobis, Max; Anderson, Kurt I.; Murphy, Paul V. (Wiley-VCH Verlag, 2014-06-11)An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migrastatin and its macroketone analogue is described; Brown alkoxyallylation is the key step for this synthesis. The macroketone ...