Browsing School of Chemistry by Author "Hu, Yun"
Now showing items 1-3 of 3
-
Effects of ball-milling and cryomilling on sulfamerazine polymorphs: A quantitative study
MacFhionnghaile, Pól; Hu, Yun; Gniado, Katarzyna; Curran, Sinead; McArdle, Patrick; Erxleben, Andrea (Elsevier, 2014-04-11)The effects of ball-milling and cryomilling on sulfamerazine forms I and II (SMZ FI, FII) were investigated using X-ray powder diffraction, infrared and near-infrared (NIR) spectroscopy. Cryomilling resulted in a complete ... -
Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug
Hu, Yun; MacFhionnghaile, Pól; Caron, Vincent; Tajber, Lidia; Healy, Anne Marie; Erxleben, Andrea; McArdle, Patrick (Elsevier, 2012-10-09)The formation and physical stability of amorphous sulfathiazole obtained from polymorphic forms I and III by cryomilling was investigated by X-ray powder diffraction (XRPD) and near-infrared (NIR) spectroscopy. Principal ... -
Solid-state transformations of sulfathiazole polymorphs: The effects of milling and humidity
Hu, Yun; Erxleben, Andrea; Hodnett, Kieran; Li, Boyan; McArdle, Patrick; Rasmuson, Åke C.; Ryder, Alan G. (American Chemical Society, 2013-07-11)The effect of milling on the transitions of sulfathiazole polymorphs in the absence and presence of solvent and excipients was monitored by X-ray powder diffraction (XRPD), attenuated total reflectance infrared (ATR-IR), ...