Browsing School of Chemistry by Title
Now showing items 277-296 of 360
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RAFT polymerization in supercritical carbon dioxide based on an induced precipitation approach: synthesis of 2-ethoxyethyl methacrylate/acrylamide block copolymers
(Wiley, 2015-05-13)A new controlled/living heterogeneous polymerization technique using RAFT in benign supercritical CO2 is described involving the formation of monomer-swollen seed particles by precipitation of macroRAFT agent prior to ... -
Rapid characterization and quality control of complex cell culture media solutions using Raman spectroscopy and chemometrics
(2010)The use of Raman spectroscopy coupled with chemometrics for the rapid identification, characterization, and quality assessment of Complex cell culture media components used for industrial mammalian cell culture was ... -
A rapid fluorescence based method for the quantitative analysis of cell culture media photo-degradation
(Elsevier (Science Direct), 2013-11-21)Cell culture media are very complex chemical mixtures that are one of the most important aspects in biopharmaceutical manufacturing. The complex composition of many media leads to materials that are inherently unstable and ... -
Rapid hydrolysis of phosphate monoesters by zirconium(IV) complexes in neutral solution
(2012)Three zirconium(IV) complexes (1-3) with mono- and dinucleating tripodal ligands are reported that promote the hydrolysis of the phosphate monoesters p-nitrophenyl phosphate (NPP) and phenyl phosphate (PP) in neutral ... -
Rapid quantification of tryptophan and tyrosine in chemically defined cell culture media using fluorescence spectroscopy
(2012)The rapid and inexpensive analysis of the complex cell culture media used in industrial mammalian cell culture is required for quality and variance monitoring. Excitation-emission matrix (EEM) spectroscopy combined with ... -
Rate constant calculations of H-Atom abstraction reactions from ethers by H(O) over dot(2) radicals
(American Chemical Society, 2014-01-31)In this work, we detail hydrogen atom abstraction reactions from six ethers by the hydroperoxyl radical, including dimethyl ether, ethyl methyl ether, propyl methyl ether, isopropyl methyl ether, butyl methyl ether, and ... -
An RCM experimental and modeling study on CH4 and CH4/C2H6 oxidation at pressures up to 160 bar
(Elsevier, 2017-06-13)The oxidation of CH4 and CH4/C2H6 mixtures were studied at pressures relevant to knocking in large bore natural gas engines. The experiments were carried out in a rapid compression machine (RCM) at end of compression (EOC) ... -
Recent advances in artificial photosynthetic systems at Newcastle University
(Elsevier, 2016-04-08)This review covers the most significant research done by the group of scientists working at Newcastle University during the last five years in the area of artificial photosynthesis. In particular, it tackles the aspects ... -
Regiospecific anomerisation of acylated glycosyl azides and benzoylated disaccharides by using TiCl4.
(Wiley, 2013-10-25)Chelation induced anomerisation is promoted when Lewis acids, such as TiCl4 or SnCl4 , coordinate to the pyranose ring oxygen atom and another site, giving rise to endocyclic cleavage and isomerisation to the more stable ... -
Relaxed but highly compact diansa metallacyclophanes
(American Chemical Society, 2011-09-09)A series of monoansa [μ-1,1′-PR-3,3′-Co(1,2-C2B9H10)2]− and diansa [8,8′-μ-(1″,2″-benzene)-μ-1,1′-PR-3,3′-Co(1,2-C2B9H9)2]− (R = Ph, tBu) cobaltabisdicarbollidephanes have been synthesized, characterized and studied by ... -
Revealing biomedically relevant cell and lectin type-dependent structure–activity profiles for glycoclusters by using tissue sections as an assay platform
(Royal Society of Chemistry, 2018-08-14)The increasing realization of the involvement of lectin-glycan recognition in (patho)physiological processes inspires envisioning therapeutic intervention by high-avidity/specificity blocking reagents. Synthetic glycoclusters ... -
Revisiting the kinetics and thermodynamics of the low-temperature oxidation pathways of alkanes: a case study of the three pentane isomers
(American Chemical Society, 2015-03-23)This paper describes our developing understanding of low-temperature oxidation kinetics. We have investigated the ignition of the three pentane isomers in a rapid compression machine over a wide range of temperatures and ... -
A route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin derivatives with quaternary centers adjacent to the ring nitrogen from Methyl α-d-Mannopyranoside
(Wiley, 2020-02-03)6-Alkylated-8-azido-1,6-octadiene derivatives were prepared from methyl α-D-mannopyranoside. The sequence to allylic azide precursors included a Horner-Wadsworth-Emmons reaction with a concomitant epimerization that ... -
Ruthenium-centred btp glycoclusters as inhibitors for Pseudomonas aeruginosa biofilm formation
(Royal Society of Chemistry, 2021-05-04)Carbohydrate-decorated clusters (glycoclusters) centred on a Ru(II) ion were synthesised and tested for their activity against Pseudomonas aeruginosa biofilm formation. These clusters were designed by conjugating a range ... -
Salts, binary and ternary cocrystals of pyrimethamine: mechanosynthesis, solution crystallization and crystallization from the gas phase
(American Chemical Society, 2020-11-24)A series of salts and binary and ternary cocrystals of the antimalaria drug pyrimethamine (PYR) are reported. PYR has a donor–acceptor–donor (DAD) and a donor–acceptor (DA) binding site, and cocrystallization experiments ... -
Scaling behavior of polymers at liquid/liquid interfaces
(American Chemical Society, 2015-09-14)The dynamics of a polymer chain confined in a soft 2D slit formed by two immiscible liquids is studied by means of molecular dynamics simulations. We show that the scaling behavior of a polymer confined between two liquids ... -
Simplified approach to the prediction and analysis of temperature inhomogeneity in rapid compression machines
(American Chemical Society, 2015-11-03)Substantial progress has been made in understanding and reducing temperature inhomogeneity in rapid compression machines (RCMs) with the help of computational modeling. To date, however, it has not been possible to investigate ... -
A single pulse shock tube study of pentene isomer pyrolysis
(Elsevier, 2020-08-02)A single-pulse shock tube study of the four pentene isomers is carried out at 2¿±¿0.16¿bar and 900¿1600¿K. C1 to C6 species profiles were recorded using gas chromatography mass spectrometry analyses. The species are ... -
A six-compound, high performance gasoline surrogate for internal combustion engines: Experimental and numerical study of autoignition using high-pressure shock tubes
(Elsevier, 2019-10-25)This paper presents experimental and modeling data for the autoignition of a novel, six-component, high performance gasoline surrogate fuel comprising ethanol, n-heptane, i-octane, 1-hexene, methylcyclohexane, and toluene ... -
Size exclusion chromatography for screening yeastolate used in cell culture media
(Elsevier, 2023-09-18)Yeastolate is often used as a media supplement in industrial mammalian cell culture or as a major media component for microbial fermentations. Yeastolate variability can significantly affect process performance, but analysis ...