Browsing by Author "Yaszemski, Michael J."
Now showing items 1-3 of 3
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Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord
Madigan, Nicolas N.; Chen, Bingkun K.; Knight, Andrew M.; Rooney, Gemma E.; Sweeney, Eva; Kinnavane, Lisa; Yaszemski, Michael J.; Dockery, Peter; O'Brien, Timothy; McMahon, Siobhan S.; Windebank, Anthony J. (Mary Ann Liebert, 2014-08-08)The use of multichannel polymer scaffolds in a complete spinal cord transection injury serves as a deconstructed model that allows for control of individual variables and direct observation of their effects on regeneration. ... -
GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats
Chen, Bingkun K.; Madigan, Nicolas N.; Hakim, Jeffrey S.; Dadsetan, Mahrokh; McMahon, Siobhan S.; Yaszemski, Michael J.; Windebank, Anthony J. (Wiley, 2017-03-10)Positively-charged oligo[poly(ethylene glycol)fumarate] (OPF+) is a biodegradable hydrogel used for spinal cord injury repair. We compared scaffolds containing primary Schwann cells (SCs) to scaffolds delivering SCs ... -
Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels
Rooney, Gemma E.; Knight, Andrew M.; Madigan, Nicolas N.; Gross, LouAnn; Chen, BingKun; Giraldo, Catalina Vallejo; Seo, Seungmae; Nesbitt, Jarred J.; Dadsetan, Mahrokh; Yaszemski, Michael J.; Windebank, Anthony J. (Mary Ann Liebert Inc, 2011-05-01)This study describes the use of oligo [(polyethylene glycol) fumarate] (OPF) hydrogel scaffolds as vehicles for sustained delivery of dibutyryl cyclic adenosine monophosphate (dbcAMP) to the transected spinal cord. dbcAMP ...