Now showing items 1-7 of 7

    • A detailed appraisal of mesocolic lymphangiology - an immunohistochemical and stereological analysis 

      Culligan, Kevin; Sehgal, Rishabh; Mulligan, Daniel; Dunne, Colum; Walsh, Stewart; Quondamatteo, Fabio; Dockery, Peter; Coffey, J. Calvin (Wiley-Blackwell, 2014-07-19)
      Inadequate resection of the adjoining mesentery is associated with adverse outcome for colon cancer. Disruption of the integrity of the mesenteric lymphatic package has been implicated in this, though not proven. Recent ...
    • Ambra1 links autophagy to cell proliferation and tumorigenesis by promoting c-myc dephosphorylation and degradation 

      Cianfanelli, Valentina; Fuoco, Claudia; Lorente, Mar; Salazar, Maria; Quondamatteo, Fabio; Gherardini, Pier Federico; De Zio, Daniela; Nazio, Francesca; Antonioli, Manuela; D’Orazio, Melania; Skobo, Tatjana; Bordi, Matteo; Rohde, Mikkel; Dalla Valle, Luisa; Helmer-Citterich, Manuela; Gretzmeier, Christine; Dengjel, Joern; Fimia, Gian Maria; Piacentini, Mauro; Di Bartolomeo, Sabrina; Velasco, Guillermo; Cecconi, Francesco (Springer Nature, 2014-12-01)
      Inhibition of a main regulator of cell metabolism, the protein kinase mTOR, induces autophagy and inhibits cell proliferation. However, the molecular pathways involved in the cross-talk between these two mTOR-dependent ...
    • Analysis of the role of Rho GTPases in epithelial cells 

      Stanley, Alanna (2014-11-19)
      Rho GTPases are a family of small GTP binding proteins that function as molecular switches for the control of a variety of fundamental cellular processes, and therefore represent potentially vital proteins for skin ...
    • Fibrillin-1 in incisional hernias: an immunohistochemical study in scar and non-scar regions of human skin and muscle fasciae 

      Fricke, Martin; Langer, Claus; Brunner, Edgar; Sakai, Lynn Y.; Füzesi, Laszlo; Reinhardt, Dieter P.; Quondamatteo, Fabio (Wiley-Blackwell, 2008-05-01)
      Incisional hernias represent one of the most common complications after laparotomy. Specific pre-operative risk factors have not yet been identified. Recent studies indicate that changes in extracellular matrix components ...
    • Rac1 in keratinocytes regulates crosstalk to immune cells by arp2/3-dependent control of stat1 

      Pedersen, Esben; Wang, Zhipeng; Stanley, Alanna; Peyrollier, Karine; Rösner, Lennart M.; Werfel, Thomas; Quondamatteo, Fabio; Brakebusch, Cord (The Company of Biologists, 2012-09-06)
      Crosstalk between keratinocytes and immune cells is crucial for the immunological barrier function of the skin, and aberrant crosstalk contributes to inflammatory skin diseases. Using mice with a keratinocyte-restricted ...
    • The anatomy and physiology of the venous foot pump 

      Corley, Gavin J.; Broderick, Barry J.; Nestor, Sarah M.; Breen, Paul P.; Grace, Pierce A.; Quondamatteo, Fabio; Ólaighin, Gearóid (Wiley-Blackwell, 2009-12-02)
    • The mesocolon 

      Culligan, Kevin; Walsh, Stewart; Dunne, Colum; Walsh, Michael; Ryan, Siobhan; Quondamatteo, Fabio; Dockery, Peter; Coffey, J. Calvin (Ovid Technologies (Wolters Kluwer Health), 2014-12-01)
      Background: Colonic mobilization requires separation of mesocolon from underlying fascia. Despite the surgical importance of planes formed by these structures, no study has formally characterized their microscopic features. ...