Browsing by Subject "Neuroimaging"
Now showing items 1-5 of 5
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Investigating the genetics of deep learning derived neuro imaging phenotypes of brain disorders
(NUI Galway, 2024-04-17)Brain disorders are collections of debilitating phenotypes that can affect cognition and general life quality via a myriad of symptoms, including mood swings, memory loss, altered thought processes, and psychosis. Despite ... -
Neuroanatomical dysconnectivity in bipolar disorder
(2016-10-13)Bipolar Disorder (BD) is a major psychotic illness characterized by cyclic mood dysregulation. The dysconnectivity hypothesis suggests that psychotic illnesses arise not from regionally specific focal pathophysiology, but ... -
Neurocognitive effects of risk variants for psychosis: neuropsychological and neuroimaging studies of variants and pathways
(2017-07-19)Schizophrenia is a complex, highly polygenic brain disorder. Cognitive deficits in schizophrenia are among the most disabling symptoms, and as of yet, have no effective treatment. Investigating the effect of genetic variants ... -
Regulation of emotion and cholinergic system connectivity in bipolar disorder
(NUI Galway, 2019-10-04)Background: The human brain comprises distributed cortico-subcortical regions that are structurally and functionally connected into a network that is known as the human connectome. Understanding how connections between ... -
White matter organisation in the human brain: diffusion MRI investigation of microstructural alterations in chronic schizophrenia and post-mortem validation
(2014-08-29)Schizophrenia is a chronic and disabling mental disorder affecting 0.7% of the worldwide population, characterised by psychotic symptoms such as delusions, hallucinations, disorganised speech and behaviour, and by social ...