Browsing by Author "Karlsson, Niclas G"
Now showing items 1-4 of 4
-
N- and O- linked Glycosylation, Developing Mass Spectrometric Strategies for the Characterisation of Glyco-epitopes
Kenny, Diarmuid T (2012-12-10)The overall goal of this thesis was to adopt a liquid chromatography-mass spectrometry (LC-MS) platform for glycomic analysis of glycoproteins. In particular we were interested in characterizing complex glycomic samples ... -
O-linked oligosaccharides from salivary agglutinin: helicobacter pylori binding sialyl-lewis x and lewis b are terminating moieties on hyperfucosylated oligo-n-acetyllactosamine
Issa, Samah; Moran, Anthony P; Ustinov, Sergey N; Lin, Jack Han-Hsing; Ligtenberg, Antoon J; Karlsson, Niclas G (Oxford University Press (OUP), 2010-04-29)Salivary agglutinin plays a vital biological role modulating the protective effect in the oral cavity by interacting with a broad range of oral pathogens. Here, we describe the first characterization of the O-linked ... -
Presence of terminal n-acetylgalactosamineβ1-4n-acetylglucosamine residues on o-linked oligosaccharides from gastric muc5ac: involvement in helicobacter pylori colonization?
Kenny, Diarmuid T; Skoog, Emma C; Lindén, Sara K; Struwe, Weston B; Rudd, Pauline M; Karlsson, Niclas G (Oxford University Press (OUP), 2012-04-26)Isolation of MUC5AC mucins from the gastric mucosa from two secretor individuals (one from normal mucosa from a patient with gastric cancer and one from a control) showed different abilities to bind and induce the proliferation ... -
Salivary muc7 is a major carrier of blood group i type o-linked oligosaccharides serving as the scaffold for sialyl lewis x
Karlsson, Niclas G; Thomsson, Kristina A (Oxford University Press (OUP), 2008-11-29)Isolation of salivary MUC7 with gel electrophoresis allowed analysis by LC-MS and LC-MS(2) of released O-linked oligosaccharides and a thorough description of the glycosylation of this molecule, where high-molecular-weight ...