Browsing by Author "Jaafar, Rola"
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Pro-survival pathways in triple negative breast cancer: Focus on the roles of RIP2 and HSPB1
Jaafar, Rola (2016-10-10)Triple negative breast cancers (TNBC) lack estrogen and progesterone receptors, and HER-2 markers rendering them resistant to current targeted therapies. Most TNBCs show basal-like characteristics and the terms TNBC and ... -
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells
Jaafar, Rola; Mnich, Katarzyna; Dolan, Sarah; Hillis, Jennifer; Almanza, Aitor; Logue, Susan E.; Samali, Afshin; Gorman, Adrienne M. (Elsevier, 2018-02-06)Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ...