Browsing by Author "IRCSET"
Now showing items 1-20 of 47
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Advances in the testing of stereo image acquisition devices
Andorko, Istvan (2014-01-04)The core problem addressed in the current thesis is to provide a novel test bed for depth map generation and stereo image-based algorithms. The test bed comprises of elements such as (i) the choice and calibration of ... -
Analysis of gene regulation using high throughput genomics
Paul, Geeleher (2012-10-23)The recent development of high-throughput genomics techniques and their subsequent applications have completely transformed the study of biology. The analysis, interpretation and storage of the resulting large volumes of ... -
Biochemical and functional characterization of human MSL2
Moravcova, Simona (2013-04-10)DNA in Eukaryotic cells is complexed with histone proteins to form chromatin. This mediates DNA packaging into the nucleus but also facilitates the regulation of all DNA-templated processes, including transcription, ... -
A Biomaterials Approach for an Ex-Vivo Multiple Sclerosis Model of Inflammatory Demyelination
Mathew, Asha (2013-10-03)Multiple sclerosis (MS) is characterised by the presence of inflammatory demyelinating foci throughout the brain and spinal cord, accompanied by axonal and neuronal damage. Although inflammatory processes are thought to ... -
Characterisation of novel Histone H3 RAD9 mutants defective in the DNA damage response in Saccharomyces cerevisiae
Walsh, Mary (2013-02-28)The DNA damage response (DDR) is a signal transduction cascade, which regulates cell cycle progression, gene transcription and DNA repair. Histones also play a vital role in the activation of the DDR and have been shown ... -
Chironomid response to prehistoric farming in northwest Ireland
Taylor, Karen (2017-12-20)This article-based PhD thesis explored the utility and performance of chironomid (Diptera: Chironomidae) autecology in the investigation of prehistoric farming impacts on freshwater lake systems. Chironomid subfossils, ... -
Classification Problems for Finite Linear Groups
Hurley, Barry (2013-03-08)This thesis is concerned with classification problems for finite linear groups. Our main concern is with groups of prime degree, and groups defined over finite fields and fields of zero characteristic. We use the computational ... -
A comprehensive flow-cytometric analysis of graft infiltrating lymphocytes, draining lymph nodes and serum during the rejection phase in a fully allogeneic rat cornea transplant model
Maenz, Martin; Morcos, Mourice; Ritter, Thomas (PubMed Central, 2011)Purpose: To establish a cornea transplant model in a pigmented rat strain and to define the immunologic reaction toward corneal allografts, by studying the cellular and humoral immune response after keratoplasty. Methods:Full ... -
A computational investigation of the laser bonding of balloon catheters
Ryan, Enda (2015-09-28)The balloon catheters produced by Boston Scientific are manufactured using a laser bonding process. The behaviour of the materials during this laser welding process is not very well understood. In this work a computational ... -
Controls on upper Viséan (Carboniferous) depositional environments in Ireland
Barham, Milo (2010-11-02)The lithostratigraphy and fauna of Carboniferous sedimentary sequences in northwest and southwest Ireland were investigated to reconstruct how and why palaeoenvironments were changing throughout the upper Viséan and ... -
Cortical Bone Fracture and Orthopaedic Fixation Devices: An Experimental and Computational Investigation
Feerick, Emer M (2012-09-28)An experimental and computational investigation of cortical bone failure mechanisms has been conducted in this thesis. Firstly, a computational comparison of four methods of proximal humeral fracture fixation was conducted. ... -
Cycloaddition reactions of imidazolium and phthalazinium dicyanomethanide 1,3-dipoles: synthesis, mechanism and the effect of water
Moloney, Eamon (2017-09-28)The cycloaddition reactions of imidazolium-3-dicyanomethanide 1,3-dipoles with electron poor alkene and alkyne dipolarophiles were explored. The reactions of these azolium 1,3-dipoles with alkyne dipolarophiles generated ... -
Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach
Simpkin, Andrew (2010-12-20)In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ... -
The Design, Development and Validation of a Wearable Behaviour Monitor for the Autonomous Assessment of the Functional Health of Older Adults
Lowe, Shane Alan (2013-12-23)Functional ability describes a person's capability to perform those tasks that are necessary to live independently. It is a proven predictor of functional decline, the need for hospitalisation and institutionalisation ... -
Development of a nested 3D hydrodynamic model for tidal turbine impact assessment
Coppinger, Darren (2016-05-12)Tidal current energy resources have the potential to provide a sizable proportion of our future energy requirements. However, significant questions still exist on the impacts of tidal turbines on the hydrodynamic environment. ... -
Ex-vivo generation of regulatory T-cells expressing transcription factor foxp3 and their application in cornea transplantation
Maenz, Martin (2011-05-27)This project investigated the therapeutic potential of allo-antigen specific regulatory T-cells in the context of penetrating keratoplasty. Two methods of ex-vivo generation of T regulatory cells have been explored in ... -
Extensions and Applications of Survival Trees in Medical Data
Alvarez-Iglesias, Alberto (2012-09-17)Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ... -
Field and geochemical studies of the Galway granite batholith - the Kilkieran sector, Connemara, western Ireland
Hunt, Jon (2015-04-24)The late-Caledonian granites of south Connemara occupy a key location in the western Irish Caledonides. The granites comprise the Galway Granite Batholith and its satellite plutons of Roundstone, Inish, Omey and Letterfrack. ... -
Functional genomics of microrna- directed regulation of tumorigenesis in human cancer cells
Selcuklu, Duygu (2011-09-30)In the past few decades, microRNAs emerged as key regulators of gene expression in many fundamental biological processes such as development and differentiation as well as diseases. There are thousands of microRNAs that ... -
Graph topology and the evolution of cooperation
Li, Menglin (2015-01-31)It has been shown that the graph topology can influence the level of cooperation in evolutionary games. Previous research showed that graphs like scale-free networks and small-world networks are more useful in maintaining ...