Browsing by Author "Hillis, Jennifer"

Now showing items 1-3 of 3

    • Neurotrophic signalling and inhibition in breast cancer and chronic lymphocytic leukaemia 

      Hillis, Jennifer (2016-01-15)
      Neurotrophins are important growth factors for neuronal cells. They interact with the Trk kinase receptors and the p75NTR receptor to induce several signaling pathways. Neurotrophins and their receptors are known regulators ...

    • Neurotrophins and B-cell malignancies 

      Gorman, Adrienne; Hillis, Jennifer; O'Dwyer, Michael (Springer Verlag, 2015-09-23)
      Neurotrophins and their receptors act as important proliferative and pro-survival factors in a variety of cell types. Neurotrophins are produced by multiple cell types in both pro and mature forms, and can act in an autocrine ...

    • RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells 

      Jaafar, Rola; Mnich, Katarzyna; Dolan, Sarah; Hillis, Jennifer; Almanza, Aitor; Logue, Susan E.; Samali, Afshin; Gorman, Adrienne M. (Elsevier, 2018-02-06)
      Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ...