Browsing by Author "Higgins, Owen"
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Development of a rapid recombinase polymerase amplification assay for the detection of Streptococcus pneumoniae in whole blood
Clancy, Eoin; Higgins, Owen; Boo, Teck Wee; Cormican, Martin; Barry, Thomas; Smith, Terry J. (BioMed Central, 2015-10-29)Background: Streptococcus pneumoniae is an important cause of microbial disease in humans. The introduction of multivalent vaccines has coincided with a dramatic decrease in the number of pneumococcal-related deaths. In ... -
Development of a rapid recombinase polymerase amplification assay for the detection of streptococcus pneumoniae in whole blood
Clancy, Eoin; Higgins, Owen; Forrest, Matthew S.; Boo, Teck Wee; Cormican, Martin; Barry, Thomas; Piepenburg, Olaf; Smith, Terry J. (Springer Nature, 2015-10-29)Background: Streptococcus pneumoniae is an important cause of microbial disease in humans. The introduction of multivalent vaccines has coincided with a dramatic decrease in the number of pneumococcal-related deaths. In ... -
Evaluation of an internally controlled multiplex tth endonuclease cleavage loop-meditated isothermal amplification (tec-lamp) assay for the detection of bacterial meningitis pathogens
Higgins, Owen; Clancy, Eoin; Cormican, Martin; Boo, Teck; Cunney, Robert; Smith, Terry (MDPI AG, 2018-02-09)Bacterial meningitis infection is a leading global health concern for which rapid and accurate diagnosis is essential to reduce associated morbidity and mortality. Loop-mediated isothermal amplification (LAMP) offers an ... -
Novel multiplex isothermal nucleic acid amplification technologies for the detection of bacterial meningitis associated pathogens
Higgins, Owen (NUI Galway, 2019-02-28)Infectious diseases, caused by pathogenic microorganisms such as bacteria, fungi or viruses, are a leading cause of significant global morbidity and mortality, with over 10 million associated deaths reported each year. ...