Now showing items 1-4 of 4

    • Gene therapy: pursuing restoration of dermal adhesion in recessive dystrophic epidermolysis bullosa 

      Cutlar, Lara; Greiser, Udo; Wang, Wenxin (Wiley-Blackwell, 2013-12-30)
      The replacement of a defective gene with a fully functional copy is the goal of the most basic gene therapy. Recessive dystrophic epidermolysis bullosa (RDEB) is characterised by a lack of adhesion of the epidermis to the ...
    • Genetically Modified Mesenchymal Stem 

      Griffin, Matthew; Greiser, Udo; Barry, Frank; O'Brien, Timothy; Ritter, Thomas (2010-03)
      Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential to differentiate into various tissues of mesodermal origin. They can be isolated from bone marrow and other tissues and have the ...
    • Liposomal gene delivery mediated by tissue-engineered scaffolds 

      Kulkarni, Mangesh; Greiser, Udo; O’Brien, Timothy; Pandit, Abhay (Elsevier BV, 2010-01-01)
      In the absence of any ideal gene delivery carrier despite the recent explosion of novel carrier systems, the current trend is to explore the complementary synergy promised by a combination of delivery systems such as ...
    • Nonviral methods for inducing pluripotency to cells 

      O'Doherty, Ryan; Greiser, Udo; Wang, Wenxin (Hindawi Limited, 2013-01-01)
      The concept of inducing pluripotency to adult somatic cells by introducing reprogramming factors to them is one that has recently emerged, gained widespread acclaim and garnered much attention among the scientific community. ...