Browsing by Author "Dennedy, Michael Conall"
Now showing items 1-6 of 6
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Atlantic-dip: raised maternal body mass index (bmi) adversely affects maternal and fetal outcomes in glucose-tolerant women according to international association of diabetes and pregnancy study groups (iadpsg) criteria
Dennedy, Michael Conall; Avalos, Gloria; O'Reilly, Michael W.; O'Sullivan, Eoin P.; Gaffney, Geraldine; Dunne, Fidelma (The Endocrine Society, 2012-04-01)Context: Raised maternal body mass index (BMI) in association with hyperglycemia is associated with adverse pregnancy outcome. The contribution of raised BMI as an independent risk factor for adverse pregnancy outcome is ... -
An investigation of the immunometabolic interactions of obesity
Dennedy, Michael Conall (2013-09-04)Human monocytes are classified as classical, intermediate and non-classical according to their surface expression of CD14 and CD16. They also represent precursors to atherogenic foam cells and macrophages in metabolically ... -
The maternal and fetal impacts of obesity and gestational diabetes on pregnancy outcome
Dennedy, Michael Conall; Dunne, Fidelma (2010)Obesity has reached pandemic proportions and is of growing concern worldwide. Adverse health outcomes associated with a raised body mass index present the greatest challenge currently facing clinicians across all ... -
The role of the liver X receptor in mitotane therapy in adrenocortical carcinoma
Warde, Kate (NUI Galway, 2020-08-12)Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with limited treatment options. The Liver X Receptor α (LXRα) is highly expressed in the adrenal cortex, and functions to regulate cholesterol and lipid ... -
Subtotal ablation and hyperthermia in the adrenal cortex
Donlon, Padraig (NUI Galway, 2021-08)Primary aldosteronism (PA) accounts for 5–12% of all hypertension and confers a higher risk for cardiovascular and cerebrovascular complications compared to age and blood pressure (BP) matched essential hypertension. PA ... -
Technological requirements for microwave ablation of adrenal masses
Fallahi, Hojjatollah; Shahzad, Atif; Clausing, Daniel; O’Halloran, Martin; Dennedy, Michael Conall; Prakash, Punit (IEEE, 2017)Microwave thermal ablation is under consideration for minimally invasive treatment of bilateral adrenal adenomas, symptomatic of Conn's syndrome. Currently available microwave technologies are ill-suited to precise ablation ...