Browsing by Author "Beckman Fund Scholarship"
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Genetic analysis of ATR, a central regulator of genome stability.
Llorens-Agost, Marta (2016-05-11)To protect the DNA against the constant assaults of endogenous and environmental agents, cells have developed conserved signaling pathways, known as the DNA damage response. Such responses are important to maintain genome ... -
The kinesin KIF18B interacts with 53BP1 and is required for efficient double strand break repair
Frizzell, Louise (2015-11-19)Genetic changes can lead to detrimental genomic instability, mutagenesis, oncogenesis and premature aging. The DNA damage response (DDR) is responsible for safeguarding the genome from such harmful alterations. 53BP1 ...