Browsing by Author "Barron, Valerie"
Now showing items 1-7 of 7
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Biomodels of bone: a review
Lohfeld, Stefan; Barron, Valerie; McHugh, Peter (Springer, 2005)In this paper, a definition of a biomodel is presented, based on which different specific types of biomodels are identified, viz., virtual biomodels, computational biomodels, and physical biomodels. The paper then focuses ... -
Evaluation of cartilage repair by mesenchymal stem cells seeded on a PEOT/PBT scaffold in an osteochondral defect
Barron, Valerie; Merghani, Khalid; Shaw, Georgina; Coleman, Cynthia; Hayes, Jessica; Ansboro, Sharon; Manian, Abi; O'Malley, Grace; Connolly, Emma; Nandakumar, Ananda; Van Blitterswijk, Clemen; Habibovic, Pamela; Moroni, Lorenzo; Shannon, Fintan; Barry, Frank; Murphy, Mary (Springer Verlag, 2015-01-15)The main objective of this study was to evaluate the effectiveness of a mesenchymal stem cell (MSC)-seeded polyethylene-oxide-terephthalate/polybutylene-terephthalate (PEOT/PBT) scaffold for cartilage tissue repair in an ... -
Evaluation of the early in vivo response of a functionally graded macroporous scaffold in an osteochondral defect in a rabbit model
Barron, Valerie; Neary, Martin; Mohamed, Khalid Merghani Salid; Ansboro, Sharon; Shaw, Georgina; O'Malley, Grace; Rooney, Niall; Barry, Frank; Murphy, Mary (Springer Verlag, 2015-10-05)Cartilage tissue engineering is a multifactorial problem requiring a wide range of material property requirements from provision of biological cues to facilitation of mechanical support in load-bearing diarthrodial joints. ... -
Fabrication, mechanical and in vivo performance of polycaprolactone/tricalcium phosphate composite scaffolds
Lohfeld, Stefan; Cahill, Senan; Barron, Valerie; McHugh, Peter (2012)This paper explores the use of selective laser sintering (SLS) for the generation of bone tissue engineering scaffolds from polycaprolactone (PCL) and PCL/tricalcium phosphate (TCP). Different scaffold designs are generated, ... -
In vitro characterization of an electroactive carbon-nanotube-based nanofiber scaffold for tissue engineering
Mackle, Joseph N.; Blond, David J.-P.; Mooney, Emma; McDonnell, Caitlin; Blau, Werner J.; Shaw, Georgina; Barry, Frank P.; Murphy, J. Mary; Barron, Valerie (Wiley-Blackwell, 2011-07-04)In an effort to reduce organ replacement and enhance tissue repair, there has been a tremendous effort to create biomechanically optimized scaffolds for tissue engineering applications. In contrast, the development and ... -
A method to fabricate small features on scaffolds for tissue engineering via selective laser sintering
Lohfeld, Stefan; Tyndyk, M.A.; Cahill, S.; Flaherty, N.; Barron, Valerie; McHugh, Peter (2010)Purpose:Selective laser sintering (SLS) is a rapid prototyping technique applied to produce tissue-engineering scaffolds from powder materials. The standard scanning technique, however, often produces struts of extensive ... -
The electrical stimulation of carbon nanotubes to provide a cardiomimetic cue to mscs
Mooney, Emma; Mackle, Joseph N.; Blond, David J.-P.; O'Cearbhaill, Eoin; Shaw, Georgina; Blau, Werner J.; Barry, Frank P.; Barron, Valerie; Murphy, J. Mary (Elsevier BV, 2012-09-01)