Browsing by Subject "ARDS"
Now showing items 1-4 of 4
-
Enhancing the efficacy and therapeutic potential of human mesenchymal stromal cells (hMSCs) in clinically relevant sepsis models
(NUI Galway, 2022-08-30)Rationale: Sepsis is a systemic inflammatory process produced by the reaction of the immune system against a pathogen. This inflammatory process produces tissue damage leading into vital organ malfunction and, if not ... -
Investigation of the role of nuclear factor kappa-B in mediating the effects of hypercapnic acidosis and mesenchymal stem cells in ventilation induced lung injury
(NUI Galway, 2016-11-08)Introduction: ARDS is a syndrome of acute respiratory failure that presents with progressive arterial hypoxemia, dyspnea, and a marked increase in the work of breathing. Mechanical ventilation is necessary to support life ... -
Therapies for acute respiratory distress syndrome: determination of the mechanisms of action of hypercapnia and the therapeutic efficacy of mesenchymal stromal cells
(2016-09-20)Rationale: Acute Respiratory Distress Syndrome (ARDS) causes severe respiratory failure and is associated with high mortality. Pharmacological therapies are non-existent and supportive ventilation treatments are limited. ... -
Understanding the Mechanisms of Action of Hypercapnic Acidosis and the Therapeutic Potential of Human Mesenchymal Stromal Cells in Diminishing Inflammation and Enhancing Repair in Acute Respiratory Distress Syndrome.
(2013-09-30)Acute respiratory distress syndrome (ARDS) is a term used to describe severe lung injury characterised by uncontrolled inflammatory response and resultant damage to endothelial and epithelial layers leading to eventual ...