Browsing by Subject "t-cell lymphoma"
Now showing items 1-2 of 2
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Clinically applicable inhibitors impacting genome stability
(MDPI AG, 2018-05-13)Advances in technology have facilitated the molecular profiling (genomic and transcriptomic) of tumours, and has led to improved stratification of patients and the individualisation of treatment regimes. To fully realize ... -
Phase ia/ii, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies
(Springer Nature, 2013-02-06)Panobinostat is a potent oral pandeacetylase inhibitor that leads to acetylation of intracellular proteins, inhibits cellular proliferation and induces apoptosis in leukemic cell lines. A phase Ia/II study was designed to ...