Browsing by Subject "multiply-charged oligonucleotides"
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Chemical selectivity of nucleobase adduction relative to in vivo mutation sites on exon 7 fragment of p53 tumor suppressor gene
(Royal Society of Chemistry (RSC), 2015-01-01)Damage to p53tumor suppressor gene is found in half of all human cancers. Databases integrating studies of large numbers of tumors and cancer cell cultures show that mutation sites of specific p53 codons are correlated ...