Browsing by Subject "human-brain"

Now showing items 1-3 of 3

    • Dopamine type-1 receptor binding in major depressive disorder assessed using positron emission tomography and [11c]nnc-112 

      Cannon, Dara M.; Klaver, Jacqueline M; Peck, Summer A; Rallis-Voak, Denise; Erickson, Kristine; Drevets, Wayne C (Springer Nature, 2008-10-22)
      The dopamine type-1 receptor has been implicated in major depressive disorder (MDD) by clinical and preclinical evidence from neuroimaging, post mortem, and behavioral studies. To date, however, selective in vivo assessment ...

    • Genetic variation in htr2a influences serotonin transporter binding potential as measured using pet and [11c]dasb 

      Laje, Gonzalo; Cannon, Dara M.; Allen, Andrew S.; Klaver, Jackie M.; Peck, Summer A.; Liu, Xinmin; Manji, Husseini K.; Drevets, Wayne C.; McMahon, Francis J. (Oxford University Press (OUP), 2010-07-01)
      In a previous study we showed that genetic variation in HTR2A, which encodes the serotonin 2A receptor, influenced outcome of citalopram treatment in patients with major depressive disorder. Since chronic administration ...

    • Response inhibition and serotonin in autism: a functional mri study using acute tryptophan depletion 

      Daly, Eileen; Ecker, Christine; Hallahan, Brian; Deeley, Quinton; Craig, Michael; Murphy, Clodagh; Johnston, Patrick; Spain, Debbie; Gillan, Nicola; Gudbrandsen, Maria; Brammer, Michael; Giampietro, Vincent; Lamar, Melissa; Page, Lisa; Toal, Fiona; Schmitz, Nicole; Cleare, Anthony; Robertson, Dene; Rubia, Katya; Murphy, Declan G. M. (Oxford University Press (OUP), 2014-07-27)
      It has been suggested that the restricted, stereotyped and repetitive behaviours typically found in autism are underpinned by deficits of inhibitory control. The biological basis of this is unknown but may include differences ...