Browsing by Subject "growth-factor receptor"
Now showing items 1-6 of 6
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Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible sers nanotags
(Springer Nature, 2014-02-12)Surface-enhanced Raman scattering (SERS) technique is becoming highly popular for multiplex biosensing due to the 'fingerprint' Raman spectra from every molecule. As a proof-of-concept, we demonstrated the actively targeted ... -
Different mechanisms for resistance to trastuzumab versus lapatinib in her2- positive breast cancers - role of estrogen receptor and her2 reactivation
(Springer Nature, 2011-11-28)Introduction: The human epidermal growth factor receptor 2 (HER2)-targeted therapies trastuzumab (T) and lapatinib (L) show high efficacy in patients with HER2-positive breast cancer, but resistance is prevalent. Here we ... -
Expression levels of her2/neu and those of collocated genes at 17q12-21, in breast cancer
(Spandidos Publications, 2012-04-23)HER2/neu is associated with poorer clinical outcome in breast cancer. Expression patterns of co-localised cancer-associated genes at 17q12-21 were examined using RT-PCR. The study group consisted of a 96-patient cohort. ... -
Intracellular mechanisms underlying the nicotinic enhancement of ltp in the rat dentate gyrus
(Wiley-Blackwell, 2009-01-01)We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long-term potentiation (LTP) in the rat dentate gyrus in vitro via activation of alpha 7 nAChR. In the present studies, ... -
On-line protein capture on magnetic beads for ultrasensitive microfluidic immunoassays of cancer biomarkers
(Elsevier BV, 2014-03-01) -
Targeting egfr with photodynamic therapy in combination with erbitux enhances in vivo bladder tumor response
(Springer Nature, 2009-01-01)Background: Photodynamic therapy (PDT) is a promising cancer treatment modality that involves the interaction of the photosensitizer, molecular oxygen and light of specific wavelength to destroy tumor cells. Treatment ...