Browsing by Subject "cytokines"
Now showing items 1-12 of 12
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Adrb3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis1
(Oxford University Press (OUP), 2008-03-01)The pathophysiology underlying preterm labor triggered by inflammatory conditions such as chorioamnionitis remains largely unclear. It has already been suggested that beta-3 adrenergic (ADRB3) agonists might be of interest ... -
Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala
(Wiley-Blackwell, 2013-08-01)The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ... -
Cytokine-induced β-cell apoptosis is no-dependent, mitochondria-mediated and inhibited by bcl-xl
(Wiley-Blackwell, 2008-04-01)Pro-inflammatory cytokines are implicated as the main mediators of beta-cell death during type 1 diabetes but the exact mechanisms remain unknown. This study examined the effects of interleukin-1 beta (IL-1 beta), ... -
Immunological research in clinical psychiatry: report on the consensus debate during the 7th expert meeting on psychiatry and immunology
(Springer Nature, 2002-01-01)There is convincing evidence that cytokines are involved in the physiology and pathophysiology of brain function and interact with different neurotransmitter and neuroendocrine pathways. The possible involvement of the ... -
Interleukin-1 accounts for intrarenal th17 cell activation during ureteral obstruction
(Elsevier BV, 2012-02-01)Interleukin 17A-secreting T-helper 17 (Th17) cells are pathogenic in inflammatory kidney diseases, but their intrarenal regulation is poorly understood. In order to better define Th17 cell dynamics during interstitial ... -
Permissive roles of cytokines interleukin-7 and flt3 ligand in mouse b-cell lineage commitment
(Proceedings of the National Academy of Sciences, 2016-11-29)Hematopoietic cells are continuously generated throughout life from hematopoietic stem cells, thus making hematopoiesis a favorable system to study developmental cell lineage commitment. The main factors incorporating ... -
Post-traumatic immunosuppression is reversed by anti-coagulated salvaged blood transfusion: deductions from studying immune status after knee arthroplasty
(Wiley-Blackwell, 2014-07-09)Major trauma increases vulnerability to systemic infections due to poorly defined immunosuppressive mechanisms. It confers no evolutionary advantage. Our objective was to develop better biomarkers of post-traumatic ... -
Recent advances in psychoneuroimmunology: inflammation in psychiatric disorders
(Walter de Gruyter GmbH, 2011-01-01)Psychiatric disorders are common and complex and their precise biological underpinnings remain elusive. Multiple epidemiological, molecular, genetic and gene expression studies suggest that immune system dysfunction may ... -
The association of serum levels of brain-derived neurotrophic factor with the occurrence of and recovery from delirium in older medical inpatients
(Hindawi Limited, 2017-01-01)Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery ... -
The monoacylglycerol lipase inhibitor jzl184 attenuates lps-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action
(Wiley-Blackwell, 2013-05-27)Background and purpose JZL184 is a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme that preferentially catabolizes the endocannabinoid 2-arachidonoyl glycerol (2-AG). Here, we have studied the effects of ... -
The role of c1q in recognition of apoptotic epithelial cells and inflammatory cytokine production by phagocytes during helicobacter pylori infection
(Springer Nature, 2015-09-08)Background: Gastric epithelial cells (GECs) undergo apoptosis during H. pylori infection and phagocytes within the mucosa engulf these cells. The recognition and clearance of apoptotic cells is a multifactorial process, ... -
Ultrasensitive microfluidic array for serum pro-inflammatory cytokines and c-reactive protein to assess oral mucositis risk in cancer patients
(Springer Nature, 2015-07-05)In addition to disease diagnostics, there is a need for biomarkers to predict severity of cancer therapy side effects such as oral mucositis. Oral mucositis is an inflammatory lesion of oral mucosa caused by high-dose ...