Browsing by Subject "Psychiatry"
Now showing items 1-9 of 9
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Cognitive course in first-episode psychosis and clinical correlates: A 4year longitudinal study using the MATRICS Consensus Cognitive Battery.
(2015-09-26)While cognitive impairments are prevalent in first-episode psychosis, the course of these deficits is not fully understood. Most deficits appear to remain stable, however there is uncertainty regarding the trajectory of ... -
The dark side of humanity: psychopathy, psychiatry and human nature
(2017-10-11)Psychopathy or antisocial personality disorder is generally conceived as a neurophysiological disorder undermining moral reasoning or sentiment, leading to behaviour which contravenes social and moral norms. This psychiatric ... -
Investigating the genetics of deep learning derived neuro imaging phenotypes of brain disorders
(NUI Galway, 2024-04-17)Brain disorders are collections of debilitating phenotypes that can affect cognition and general life quality via a myriad of symptoms, including mood swings, memory loss, altered thought processes, and psychosis. Despite ... -
Neuroanatomical dysconnectivity in bipolar disorder
(2016-10-13)Bipolar Disorder (BD) is a major psychotic illness characterized by cyclic mood dysregulation. The dysconnectivity hypothesis suggests that psychotic illnesses arise not from regionally specific focal pathophysiology, but ... -
Progression of neuroanatomical abnormalities in psychosis
(NUI Galway, 2019-12-18)Background: Structural brain changes and their cross-sectional relationships with clinical and functional measures have been demonstrated several times using magnetic resonance imaging at the onset of first-episode of ... -
Progression of neuroanatomical abnormalities in psychotic disorder and the effect of psychotropic medication
(NUI Galway, 2021-05-24)Introduction: Schizophrenia is a particularly severe and disabling mental disorder affecting 20 million people worldwide. The vast majority of structural and diffusion neuroimaging studies on neuroanatomy and cognition ... -
A prospective evaluation of involuntary admission from the viewpoint of service users
(2016-09-19)Introduction: Involuntary admission is often a traumatic experience for patients and it is associated with negative attitudes which can persist after the episode of illness has abated. Aims: The aims of the study were ... -
Quality of life in psychotic illness: baseline and prospective determinants in first episode and chronic psychosis cohorts
(2017-08-01)Abstract The overall aim of this thesis was to longitudinally assess determinants of quality of life in first episode and chronic psychosis patient cohorts. The Galway First Episode Psychosis Cohort Background: In ... -
Regulation of emotion and cholinergic system connectivity in bipolar disorder
(NUI Galway, 2019-10-04)Background: The human brain comprises distributed cortico-subcortical regions that are structurally and functionally connected into a network that is known as the human connectome. Understanding how connections between ...