Now showing items 1-2 of 2

    • Metabolism of vertebrate amino sugars withn-glycolyl groups 

      Davies, Leela R. L.; Pearce, Oliver M. T.; Tessier, Matthew B.; Assar, Siavash; Smutova, Victoria; Pajunen, Maria; Sumida, Mizuki; Sato, Chihiro; Kitajima, Ken; Finne, Jukka; Gagneux, Pascal; Pshezhetsky, Alexey; Woods, Robert; Varki, Ajit (American Society for Biochemistry & Molecular Biology (ASBMB), 2012-06-12)
      The sialic acid (Sia) N-acetylneuraminic acid (Neu5Ac) and its hydroxylated derivative N-glycolylneuraminic acid (Neu5Gc) differ by one oxygen atom. CMP-Neu5Gc is synthesized from CMP-Neu5Ac, with Neu5Gc representing a ...
    • Recombinant expression and characterization of ligand binding to mutants ff 3-O-sulphotransferase-1 

      Walsh, Niall (2014-10-21)
      Heparan Sulphate (HS) is a highly charged glycosyaminoglycan (GAG) that is closely related to Heparin, a related GAG with a higher degree of sulphation. Heparin is used in the development of anticoagulant drugs. Currently, ...