Browsing by Author "Twiner, Michael J."
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Comparative effects of the marine algal toxins azaspiracid-1, -2, and -3 on jurkat t lymphocyte cells
Twiner, Michael J.; El-Ladki, Racha; Kilcoyne, Jane; Doucette, Gregory J. (American Chemical Society (ACS), 2012-03-19)Azaspiracids (AZA) are polyether marine toxins of dinoflagellate origin that accumulate in shellfish and represent an emerging human health risk. Although monitored and regulated in many European and Asian countries, there ... -
Isolation, structure elucidation, relative lc-ms response, and in vitro toxicity of azaspiracids from the dinoflagellateazadinium spinosum
Kilcoyne, Jane; Nulty, Ciara; Jauffrais, Thierry; McCarron, Pearse; Herve, Fabienne; Foley, Barry; Rise, Frode; Crain, Sheila; Wilkins, Alistair L.; Twiner, Michael J.; Hess, Philipp; Miles, Christopher O. (American Chemical Society (ACS), 2014-11-26)We identified three new azaspiracids (AZAs) with molecular weights of 715, 815, and 829 (AZA33 (3), AZA34 (4), and AZA35, respectively) in mussels, seawater, and Azadinium spinosum culture. Approximately 700 mu g of 3 and ... -
Structure elucidation, relative lc–ms response and in vitro toxicity of azaspiracids7–10isolated from mussels (mytilus edulis)
Kilcoyne, Jane; Twiner, Michael J.; McCarron, Pearse; Crain, Sheila; Giddings, Sabrina D.; Foley, Barry; Rise, Frode; Hess, Philipp; Wilkins, Alistair L.; Miles, Christopher O. (American Chemical Society (ACS), 2015-05-27)Azaspiracids (AZAs) are marine biotoxins produced by dinoflagellates that can accumulate in shellfish, which if consumed can lead to poisoning events. AZA7-10, 7-10, were isolated from shellfish and their structures, ...