Browsing by Author "Tuite, Nina"
Now showing items 1-5 of 5
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Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae
Coughlan, Helena; Reddington, Kate; Tuite, Nina; Wee Boo, Teck; Cormican, Martin; Barrett, Louise; Smith, Terry; Clancy, Eoin; Barry, Thomas (Elsevier, 2015-06-23)Haemophilus influenzae is recognised as an important human pathogen associated with invasive infections, including bloodstream infection and meningitis. Currently used molecular-based diagnostic assays lack specificity in ... -
Comparison of established diagnostic methodologies and a novel bacterial smpB real-time PCR assay for the specific detection of haemophilus influenzae associated with respiratory tract infections
Reddington, Kate; Schwenk, Stefan; Tuite, Nina; Platt, Gareth; Davar, Danesh; Coughlan, Helena; Personne, Yoann; Enne, Virve I.; Zumla, Alimuddin; Barry, Thomas (American Society for Microbiology, 2015-06-23)Haemophilus influenzae is a significant causative agent of respiratory tract infections (RTI) worldwide. The development of a rapid H. influenzae diagnostic assay that would allow for the implementation of infection control ... -
Comparison of established diagnostic methodologies and a novel bacterialsmpbreal-time pcr assay for specific detection of haemophilus influenzae isolates associated with respiratory tract infections
Reddington, Kate; Schwenk, Stefan; Tuite, Nina; Platt, Gareth; Davar, Danesh; Coughlan, Helena; Personne, Yoann; Gant, Vanya; Enne, Virve I.; Zumla, Alimuddin; Barry, Thomas (American Society for Microbiology, 2015-06-24)Haemophilus influenzae is a significant causative agent of respiratory tract infections (RTI) worldwide. The development of a rapid H. influenzae diagnostic assay that would allow for the implementation of infection control ... -
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
Kelly, Helena; Downing, Tim; Tuite, Nina; Smith, Terry; Kerin, Michael; Dwyer, Róisín M.; Clancy, Eoin; Reddington, Kate; Barry, Thomas (Public Library of Science, 2015-09-10)Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers ... -
A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water
Minogue, Elizabeth; Tuite, Nina; Smith, Cindy J.; Reddington, Kate; Barry, Thomas (BioMed Central, 2015-02-18)Water and High Purity Water (HPW) distribution systems can be contaminated with human pathogenic microorganisms. This biocontamination may pose a risk to human health as HPW is commonly used in the industrial, pharmaceutical ...