Browsing by Author "Lindner, Robert"

Now showing items 1-2 of 2

    • A 3′-untranslated region kras variant and triple-negative breast cancer: a case-control and genetic analysis 

      Paranjape, Trupti; Heneghan, Helen; Lindner, Robert; Keane, Florence K; Hoffman, Aaron; Hollestelle, Antoinette; Dorairaj, Jemima; Geyda, Kimberly; Pelletier, Cory; Nallur, Sunitha; Martens, John WM; Hooning, Maartje J; Kerin, Michael; Zelterman, Daniel; Zhu, Yong; Tuck, David; Harris, Lyndsay; Miller, Nicola; Slack, Frank; Weidhaas, Joanne (Elsevier BV, 2011-04-01)
      Background We previously identified a functional variant in a let-7 microRNA (miRNA) complementary site in the 3'-untranslated region of the KRAS oncogene (rs61764370) which is associated with cancer. We aimed to investigate ...

    • A germline mutation in the brca13’utr predicts stage iv breast cancer 

      Dorairaj, Jemima J; Salzman, David W; Wall, Deirdre; Rounds, Tiffany; Preskill, Carina; Sullivan, Catherine AW; Lindner, Robert; Curran, Catherine; Lezon-Geyda, Kim; McVeigh, Terri; Harris, Lyndsay; Newell, John; Kerin, Michael J; Wood, Marie; Miller, Nicola; Weidhaas, Joanne B (Springer Nature, 2014-06-10)
      Background: A germline, variant in the BRCA1 3'UTR (rs8176318) was previously shown to predict breast and ovarian cancer risk in women from high-risk families, as well as increased risk of triple negative breast cancer. ...