Browsing by Author "Jost, Edgar"

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    • Drugging the unfolded protein response in acute leukemias 

      Kharabi Masouleh, Behzad; Chevet, Eric; Panse, Jens; Jost, Edgar; O’Dwyer, Michael; Bruemmendorf, Tim H.; Samali, Afshin (Springer Nature, 2015-07-16)
      The unfolded protein response (UPR), an endoplasmic reticulum (ER) stress-induced signaling cascade, is mediated by three major stress sensors IRE-1 alpha, PERK, and ATF6 alpha. Studies described the UPR as a critical ...