Browsing by Author "Curtin, William A"
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Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury
Kennedy, Muiris T; Higgins, Brendan D; Costello, Joseph F; Curtin, William A; Laffey, John G (BioMed Central Ltd., 2008-07-08)Background: Hypertonic saline (HTS) reduces the severity of lung injury in ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. However, the potential for HTS to modulate the resolution of lung ... -
Inhibition of polymethylmethacrylate particle-induced monocyte activation and il-1β and tnf-α expression by the antioxidant agent n-acetylcysteine
Mulhall, Kevin J; Curtin, William A; Given, H Frederick (Informa UK Limited, 2002-01-01)We investigated the effectiveness of an antioxidant agent, N-acetylcysteine (NAC), in suppressing macrophage activation and mediator release in response to particulate debris. Polymethylmethacrylate (PMMA) particle-stimulated ...