Browsing by Title
Now showing items 7001-7020 of 14645
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Inhibition of nedd8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
(American Society of Hematology, 2010-03-04)NEDD8 activating enzyme (NAE) has been identified as an essential regulator of the NEDD8 conjugation pathway, which controls the degradation of many proteins with important roles in cell-cycle progression, DNA damage, and ... -
Inhibition of polymethylmethacrylate particle-induced monocyte activation and il-1β and tnf-α expression by the antioxidant agent n-acetylcysteine
(Informa UK Limited, 2002-01-01)We investigated the effectiveness of an antioxidant agent, N-acetylcysteine (NAC), in suppressing macrophage activation and mediator release in response to particulate debris. Polymethylmethacrylate (PMMA) particle-stimulated ... -
Inhibition of polyomavirus DNA replication by nucleotide analogs
(2017-01-31)Polyomaviruses are non-evenloped circular DNA viruses that cause severe polyomavirus-associated diseases in immune compromised individuals. The diseases associated with these viruses have been on the rise due to myriad of ... -
Inhibition of pulmonary nuclear factor kappa-b decreases the severity of acute escherichia coli pneumonia but worsens prolonged pneumonia
(Springer Nature, 2013-01-01)Introduction: Nuclear factor (NF)-kappa B is central to the pathogenesis of inflammation in acute lung injury, but also to inflammation resolution and repair. We wished to determine whether overexpression of the NF-kappa ... -
Inhibitory effect of recombinant inos gene expression on vasomotor function of canine basilar artery
(American Physiological Society, 2002-08-22)The present study was designed to determine the effect of recombinant inducible nitric oxide (NO) synthase (iNOS) gene expression on vasomotor function in cerebral arteries. Isolated canine basilar arteries were exposed ... -
Inhomogeneous "longitudinal" circularly-polarized plane waves in anisotropic elastic crystals
(S. Hirzel verlag, Ingenta Connect, 2006)Conditions on the elastic stiffnesses of anisotropic crystals are derived such that circularly polarized longitudinal inhomogeneous plane waves with an isotropic slowness bivector may propagate for any given direction of ... -
Inhomogeneous "longitudinal" plane waves in a deformed elastic material
(Springer, 2005-01)By definition, a homogeneous isotropic compressible Hadamard material has the property that an infinitesimal longitudinal homogeneous plane wave may propagate in every direction when the material is maintained in a state ... -
Inhomogeneous deformation of brain tissue during tension tests
(Elsevier, 2012)Mechanical characterization of brain tissue has been investigated extensively by various research groups over the past 50 years. These properties are particularly important for modeling Traumatic Brain Injury (TBI). ... -
Inhomogeneous deformation of brain tissue during tension tests
(Elsevier BV, 2012-11-01) -
Inhomogeneous shear of orthotropic incompressible non-linearly elastic solids: Singular solutions and biomechanical interpretation
(Elsevier, 2009)We present a detailed study of rectilinear shear deformation in the framework of orthotropic nonlinear elasticity, under Dirichlet and mixed-boundary conditions. We take a slab made of a soft matrix, reinforced with two ... -
Initial motivation and its impact on quality and dynamics in formal youth mentoring relationships: A longitudinal qualitative study
(2017-06-23)This longitudinal qualitative study explores experiences and understandings of the mentoring role in the Big Brothers Big Sisters Czech Republic mentoring programme, using a phenomenological approach. In particular, the ... -
Initial motivation of mentors in formal youth mentoring relationships
(Routledge, 2021-06-22)The paper presents results of a phenomenological longitudinal qualitative study undertaken with mentors associated with the Big Brothers Big Sisters programme in the Czech Republic. Ten mentors were interviewed during the ... -
Initial psychometric evaluation of a psychological resilience measure for physicians
(Taylor and Francis, 2019-10-20)Measures of Psychological Resilience (PR) for use with physician populations are lacking. The objective of this study is to develop and assess the validity and internal consistency of a survey designed to measure the ... -
Initial stress symmetry and its applications in elasticity
(The Royal Society, 2015-10-28)An initial stress within a solid can arise to support external loads or from processes such as thermal expansion in inert matter or growth and remodelling in living materials. For this reason, it is useful to develop a ... -
Initial stress symmetry and its applications in elasticity
(The Royal Society, 2015-10-28)An initial stress within a solid can arise to support external loads or from processes such as thermal expansion in inert matter or growth and remodelling in living materials. For this reason, it is useful to develop a ... -
Initial stresses in elastic solids: constitutive laws and acoustoelasticity
(Elsevier BV, 2011-11-01) -
Initial stresses in elastic solids: Constitutive laws and acoustoelasticity
(2011)On the basis of the nonlinear theory of elasticity, the general constitutive equation for an isotropic hyperelastic solid in the presence of initial stress is derived. This derivation involves invariants that couple the ... -
Initial teacher education in Ireland: Structure, policy developments and implications for practice
(Bulgarian Comparative Education Society (BCES), 2014)This paper aims to provide an overview of recent policy developments in Initial Teacher Education in Ireland, their impact on practices and challenges for ITE providers and schools. It will outline and discuss recruitment ... -
Initiation of jc virus dna replication in vitro by human and mouse dna polymerase alpha-primase
(Wiley-Blackwell, 2003-05-01)Host species specificity of the polyomaviruses simian virus 40 (SV40) and mouse polyomavirus (PyV) has been shown to be determined by the host DNA polymerase alpha-primase complex involved in the initiation of both viral ...