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Now showing items 726-745 of 14644
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Allies and enemies, past and present: An analysis of the rationale for the development of universal jurisdiction over serious crimes under international law
(2017-11-08)Universal jurisdiction is a type of extraterritorial jurisdiction in international law. It permits any State to prosecute persons accused of committing certain abuses regardless of where the offence occurred and irrespective ... -
The allocation of time to non-market off-farm activities by farm household members in the West of Ireland
(2014-05-26)Community development and social support systems have evolved uniquely in rural Ireland. In response to poverty and other historical developments, dense networks of families, friends and neighbours often formed strong ... -
Allogeneic cell therapy for osteoarthritis
(2016-05-11)Osteoarthritis is a debilitating multi-factorial joint disease which currently has no cure. Due to the significant immune cell mediated component in this disease a therapy which can modulate this inflammation and promote ... -
Allogeneic chondroprogenitors display immunosuppressive properties and are non-immunogenic in vitro
(Elsevier BV, 2015-04-01) -
Allogeneic murine mesenchymal stem cells: migration to inflamed joints in vivo and amelioration of collagen induced arthritis when transduced to express ctla4ig
(Mary Ann Liebert Inc, 2013-12-15)Despite the immunosuppressive, homing, and regenerative capabilities of mesenchymal stem cells (MSCs), their ability to migrate to arthritic joints and influence the course of arthritis in vivo remains poorly understood. ... -
Allozyme variation in european lobster (homarus gammarus) throughout its distribution range
(Informa UK Limited, 2005-06-01)The European lobster, Homarus gammarus, is a high value species, which is widely distributed from the northern part of Norway to Morocco in North Africa. It is also found throughout the Mediterranean including the Aegean ... -
Allylic azide rearrangement in tandem with Huisgen cycloaddition for stereoselective annulation: synthesis of C-Glycosyl iminosugars
(American Chemical Society, 2015-12-09)Allylic azide rearrangement is used. in,tandem with. intramolecular azide-alkene cycloaddition to give a triazoline that when subsequently decomposed in the presence of a nucleophile gives piperidines. The tandem reaction ... -
Allylic azide rearrangement in tandem with intramolecular Huisgen cycloaddition for iminosugar and glycomimetic synthesis. Functionalized piperidine, pyrrolidine and pyrrolotriazoles from D-mannose
(Thieme Publishing, 2017-04-20)Intramolecular Huisgen azide-alkene cycloaddition reaction of 7-azido-hepta-1,5-diene-3,4-diols, prepared from methyl α-d-mannopyranoside, were carried out. Allylic azide rearrangement to secondary azides occurred ... -
Along the way: a multi-method examination of tourism, identity, and community values on Ireland’s Wild Atlantic Way
(NUI Galway, 2023-01-04)Background Marine and coastal tourism plays an indisputably crucial role in global tourism, yet there remains a dearth of academic attention afforded to coastal tourism trails in the Irish context. Cultural aspects of ... -
Alongshore variation of aeolian sediment transport on a beach, under offshore winds
(Elsevier BV, 2013-03-01) -
Alteration spaces: Charting the sustainability potential of large organizations
(Elsevier, 2021-10-08)Large organizations play a key role in sustainability transitions through their systems of production and consumption and their influence on wider society. Recognizing the uniqueness and complexity of structure-agency ... -
Alterations in algae biliproteins induced by freeze-drying
(Portland Press Ltd., 1985-04-01) -
Alterations in hepatic mirna expression during negative energy balance in postpartum dairy cattle
(Springer Nature, 2014-01-01)Background: Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake. During NEB the liver undergoes oxidative stress ... -
Alterations in the central opioid system following acute swim stress and olfactory bulbectomy in the rat
(Elsevier, 2019-12-13)Introduction: Stress is a major component of many animal models of depression, induced acutely as in the forced swim test, or more long-term in the olfactory bulbectomy (OB) and chronic mild stress models [1]. The central ... -
Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated disrupted-in-schizophrenia 1
(Springer Nature, 2015-05-19)Considerable evidence implicates DISC1 as a susceptibility gene for multiple psychiatric diseases. DISC1 has been intensively studied at the molecular, cellular and behavioral level, but its role in regulating brain ... -
Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function
(Oxford University Press (OUP), 2019-12-23)Mutations in genes that encode centrosomal/ciliary proteins cause severe cognitive deficits, while common single-nucleotide polymorphisms in these genes are associated with schizophrenia (SZ) and cognition in genome-wide ... -
Altered interhemispheric and temporal lobe white matter microstructural organization in severe chronic schizophrenia
(Springer Nature, 2013-10-22)Diffusion MRI investigations in schizophrenia provide evidence of abnormal white matter (WM) microstructural organization as indicated by reduced fractional anisotropy (FA) primarily in interhemispheric, left frontal and ... -
Altered linkage of hydroxyacyl chains in bacterial lipid a
(American Society for Biochemistry & Molecular Biology (ASBMB), 2010-07-02) -
Altered mechanical environment of bone cells in an animal model of short- and long-term osteoporosis
(Biophysical Society, 2015-04-07)Alterations in bone tissue composition during osteoporosis likely disrupt the mechanical environment of bone cells and may thereby initiate a mechanobiological response. It has proved challenging to characterize the ... -
Altered mechanical environment of bone cells in an animal model of short- and long-term osteoporosis
(Elsevier BV, 2015-04-01)Alterations in bone tissue composition during osteoporosis likely disrupt the mechanical environment of bone cells and may thereby initiate a mechanobiological response. It has proved challenging to characterize the ...