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Now showing items 2032-2051 of 14644
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Characterisation of peroxisome proliferator-activated receptor signalling in the midbrain periaqueductal grey of rats genetically prone to heightened stress, negative affect and hyperalgesia
(Elsevier, 2016-12-01)The stress-hyperresponsive Wistar-Kyoto (WRY) rat strain exhibits a hyperalgesic phenotype and is a useful genetic model for studying stress-pain interactions. Peroxisome proliferator-activated receptor (PPAR) signalling ... -
Characterisation of rotationally moulded polymer liners for low permeability cryogenic applications in composite overwrapped pressure vessels
(2016-09-20)Composite overwrapped pressure vessels (COPVs) have become a critical component in satellite and space applications due to their ability to store highly permeating fuels at high pressures and under cryogenic conditions. ... -
Characterisation of sex differences in behavioural domains and antidepressant response in two rat models of depression
(NUI Galway, 2018-10-17)Although the rate of depression is known to be almost twice as high in women compared to men, most evaluation of antidepressant efficacy involved only males until the early 1990s. In pre-clinical depression research male ... -
Characterisation of the cellular responses to CDC7 inhibition in breast-derived human cells
(2017-10-06)CDC7 plays a role in DNA replication initiation and cell cycle regulation. Inhibition of CDC7 kinase by siRNA triggers a p53-independent apoptotic cell death in cancer cells but not in human fibroblast suggesting this ... -
Characterisation of the differentially regulated trout protein 1 (DRTP1) gene in rainbow trout (Oncorhynchus mykiss)
(Elsevier, 2008-10-04)Increased levels of differentially regulated trout protein 1 (DRTP1) mRNA transcripts have been reported in fish after activation of the acute phase response. While the function of the DRTP1 protein still remains to be ... -
Characterisation of the molecular and functional changes exerted on human bone marrow mesenchymal stem cells by prostate cancer cells
(2016-07-01)Mesenchymal stem cells (MSCs) are a heterogenous population of multipotent cells that are capable of differentiating into osteocytes, chondrocytes and adipocytes. MSCs reside in various areas such as the bone marrow, ... -
Characterisation of three zinc finger proteins ZC3H8, ZC3H11A and ZC3H14, identified as new partners of ATM, the central regulator of biological response to DNA double strand breaks
(NUI Galway, 2019-12-16)The integrity of our genome is very important therefore, our cells have developed efficient DNA repair mechanisms to control this integrity and avoid mutations. Although the DNA double strand break response pathway is ... -
Characterisation of triple negative breast carcinoma and identification of the value of immunohistochemical markers and stromal tumour infiltrating lymphocytes
(NUI Galway, 2017-10)Breast cancer is a complex disease that encompasses multiple molecular subtypes that have different clinical behavior. The behavior can be influenced by both the characteristics of the cancer cells as well as the surrounding ... -
Characterisation of UVA-induced DNA damage responses in human skin cells
(2013-09-30)Accumulating evidence indicates that exposure to long-wavelength ultraviolet A (UVA) radiation (315-400 nm), which accounts for >95% of solar UV radiation reaching the earth's surface, is a significant risk factor for the ... -
Characterising and evaluating online communities from live microblogging user interactions
(NUI Galway, 2018-07-03)Microblogging (mainly represented by Twitter) is a type of social media that focuses on fast open real-time communication using short messages between users and their followers. This system is attractive due to its open ... -
Characterising bases of pure difference ideals
(NUI Galway, 2020-09-10)In this thesis, we study the basis sets of pure difference ideals, that is, ideals that are generated by differences of monic monomials. We examine the action of the hyperoctahedral group on the defining ideal of the Segre ... -
Characterising glyphosate exposures among amenity horticulturists using multiple spot urine samples
(Elsevier, 2018-07-08)Background Glyphosate has recently received much public attention following its Group 2A probably carcinogenic to humans classification from the International Agency for Research on Cancer. Despite the widespread ... -
Characterising occupational exposure to glyphosate among amenity horticulturists
(NUI Galway, 2018-12-19)A dearth of knowledge exists regarding occupational glyphosate exposures among amenity horticulturalists. Glyphosate is the highest volume herbicide used globally, and has recently been classified by the International ... -
Characterising the anisotropic mechanical properties of excised human skin
(2012)The mechanical properties of skin are important for a number of applications including surgery, dermatology, impact biomechanics and forensic science. In this study, we have investigated the influence of location and ... -
Characterising the effect of global and local geometric imperfections on the numerical performance of a brace member
(IOP Publishing, 2015-07-09)A numerical imperfection study is carried out on a hot rolled tubular brace member under displacement controlled amplitudes. An appropriate range of global and local imperfections is used in the finite element analyses to ... -
Characterising the energy consumption of machine tool actuator components using pattern recognition
(Elsevier BV, 2013-01-01) -
Characterising the geochemistry of the natural environment using compositional data analysis
(NUI Galway, 2021-05-31)The geochemistry of the natural environment (e.g. soils, streams, sediments and groundwater) is representative of the source(s) from which these materials are derived. In fact, a geochemical dataset is essentially a ... -
Characterising the marine Natura 2000 network for the Atlantic region
(John Wiley & Sons, Ltd., 2008)1. One of the goals for Natura 2000, a key European Community programme of nature conservation, is to produce a network of protected areas. An analysis of the Natura 2000 marine sites proposed in the most recently agreed ... -
Characteristic classes of complexified bundles
(Summer School in Algebraic Topology: Sheaf theoretic methods in the theory of characteristic classes, 2007)We examine the topological characteristic cohomology classes of complexified vector bundles . In particular, all the classes coming from real vector bundles are computed. We use characteristic classes with the ax-ioms of ... -
Characteristics of black carbon aerosol during the chinese lunar year and weekdays in xi’an, china
(MDPI AG, 2015-02-05)Black carbon (BC) aerosol plays an important role in climate forcing. The net radiative effect is strongly dependent on the physical properties of BC particles. A single particle soot photometer and a carbon monoxide ...