Browsing by Title

Now showing items 1938-1957 of 14643

    • The Celticization of the West: an Irish perspective 

      Waddell, John (1991)
      It is argued that the emergence of a Celtic language in Ireland was the culmination of a long process of social and economic interaction at an elite level between Ireland and Britain, and between these islands and adjacent ...

    • Censored: Whistleblowers and impossible speech 

      Kenny, Kate (SAGE Publications, 2017-11-10)
      What happens to a person who speaks out about corruption in their organization, and finds themselves excluded from their profession? In this article, I argue that whistleblowers experience exclusions because they have ...

    • A census of human soluble protein complexes 

      Yang, Haixuan (Elsevier, 2012-08-11)
      Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative ...

    • Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential 

      Concannon, Ruth M.; Dowd, Eilís (Medknow Publications, 2016-10-19)
      In recent times there has been an intensification of interest in the pathological role of neuroinflammation in neurodegenerative disease. Neuroprotective strategies to slow, halt or reverse neurodegeneration have not proven ...

    • Central places in a rural archaeological landscape 

      Comber, Michelle (Eagle Hill Institute, 2018)
      Archaeological survey in western Ireland has identified the existence of clusters of activity within the mapped landscapes of the 5th to 12th centuries A.D. Exploring this further, it is possible to identify elements ...

    • The centrality of the Galway hooker to dwelling in the island and coastal communities of south west Conamara 

      Ó Sabhain, Pádraig Seosamh (NUI Galway, 2019-11-30)
      Abstract This research explores the relational nature of the Galway hooker, a traditional carvel-built wooden sail-boat described by Scott (2004) as “The Workhorse of Galway Bay” (Scott, 2004, p.22). It focuses on the ...

    • Centre and norm 

      Beidleman, J.C.; Heineken, H.; Newell, M. (Cambridge University Press (CUP), 2004-06-01)
      We establish a correlation between the structures of a group of power automorphisms of some group and their mutual commutator subgroup and consider the consequences for the norm of a group, and for its capability.

    • Centrin2 regulates cp110 removal in primary cilium formation 

      Prosser, Suzanna L.; Morrison, Ciaran G. (Rockefeller University Press, 2015-03-09)
      Primary cilia are antenna-like sensory microtubule structures that extend from basal bodies, plasma membrane-docked mother centrioles. Cellular quiescence potentiates ciliogenesis, but the regulation of basal body formation ...

    • Centriolar and ciliary responses to DNA damage 

      Conroy, Pauline Ciara (2012-09-26)
      Centrosome duplication is tightly controlled and takes place only once every cell cycle. In recent years more light has been shed on the mechanism of centrosome duplication, with key players being identified and characterised. ...

    • Centriole splitting caused by loss of the centrosomal linker protein c-nap1 reduces centriolar satellite density and impedes centrosome amplification 

      Flanagan, Anne-Marie; Stavenschi, Elena; Basavaraju, Shivakumar; Gaboriau, David; Hoey, David A.; Morrison, Ciaran G. (American Society for Cell Biology (ASCB), 2017-01-18)
      Duplication of the centrosomes is a tightly regulated process. Abnormal centrosome numbers can impair cell division and cause changes in how cells migrate. Duplicated centrosomes are held together by a proteinaceous linker ...

    • Centrobin controls primary ciliogenesis in vertebrates 

      Ogungbenro, Yetunde Adesanya; Tena, Teresa Casar; Gaboriau, David; Lalor, Pierce; Dockery, Peter; Philipp, Melanie; Morrison, Ciaran G. (Rockefeller University Press, 2018-02-13)
      The BRCA2 interactor, centrobin, is a centrosomal protein that has been implicated in centriole duplication and microtubule stability. We used genome editing to ablate CNT ROB in hTERT-RPE1 cells and observed an increased ...

    • Centrobin functions in centriole duplication, primary ciliogenesis and genome maintenance 

      Adesanya, Yetunde (2018-03-06)
      The centrosome is composed of numerous proteins that make up its core structure. Other proteins also transiently localise and interact with centrosomal proteins for functional modulation. Centrobin, one of the core centrosomal ...

    • Centromere function in asymmetrically dividing Drosophila germline stem cells 

      Kochendoerfer, Antje Maria (NUI Galway, 2023-03-28)
      Germline stem cells (GSCs) undergo asymmetric cell division (ACD) to give rise to one stem cell residing in the niche and one differentiating daughter cell. The daughter cell subsequently divides through mitosis and meiosis ...

    • Centromere sliding on a mammalian chromosome 

      Purgato, Stefania; Belloni, Elisa; Piras, Francesca M.; Zoli, Monica; Badiale, Claudia; Cerutti, Federico; Mazzagatti, Alice; Perini, Giovanni; Della Valle, Giuliano; Nergadze, Solomon G.; Sullivan, Kevin F.; Raimondi, Elena; Rocchi, Mariano; Giulotto, Elena (Springer Nature, 2014-11-21)
      The centromere directs the segregation of chromosomes during mitosis and meiosis. It is a distinct genetic locus whose identity is established through epigenetic mechanisms that depend on the deposition of centromere-specific ...

    • Centrosome amplification in cho and dt40 cells by inactivation of cyclin-dependent kinases 

      Steere, Nathan; Wagner, Michael; Beishir, Stephen; Smith, Ewan; Breslin, Loretta; Morrison, Ciaran G.; Hochegger, Helfrid; Kuriyama, Ryoko (Wiley-Blackwell, 2011-07-29)

    • Centrosome amplification induced by dna damage occurs during a prolonged g2 phase and involves atm 

      Dodson, Helen; Bourke, Emer; Jeffers, Liam J; Vagnarelli, Paola; Sonoda, Eiichiro; Takeda, Shunichi; Earnshaw, William C; Merdes, Andreas; Morrison, Ciaran (Wiley-Blackwell, 2004-09-09)
      Centrosomes are the principal microtubule organising centres in somatic cells. Abnormal centrosome number is common in tumours and occurs after gamma-irradiation and in cells with mutations in DNA repair genes. To investigate ...

    • Centrosome cohesion: functions of C-NAP1 

      Flanagan, Anne-Marie (2016-01-07)
      Double stranded DNA encodes the genetic material of the cell. Replication and segregation cycles are regulated in order to maintain the integrity of the DNA sequence from one cell cycle to the next. Detection of lesions ...

    • Ceol agus amhránaíocht 

      Ó Laoire, Lillis (Comhairle Bhéaloideas Éireann (Four Courts), 2013)
      Discussion of transmission and performance of traditional song.

    • Cep164-null cells generated by genome editing show a ciliation defect with intact dna repair capacity 

      Daly, Owen M.; Gaboriau, David; Karakaya, Kadin; King, Sinéad; Dantas, Tiago J.; Lalor, Pierce; Dockery, Peter; Krämer, Alwin; Morrison, Ciaran G. (The Company of Biologists, 2016-03-10)
      Primary cilia are microtubule structures that extend from the distal end of the mature, mother centriole. CEP164 is a component of the distal appendages carried by the mother centriole that is required for primary cilium ...

    • Cephalopod life history, ecology and fisheries: an introduction 

      Guerra, Ángel; Allcock, A. Louise; Pereira, João (Elsevier BV, 2010-11-01)