Browsing by Title
Now showing items 1359-1378 of 4501
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An Evolutionary Approach to Automatic Kernel Construction
(2006)Abstract. Kernel-based learning presents a unified approach to machine learning problems such as classification and regression. The selection of a kernel and associated parameters is a critical step in the application of ... -
Evolutionary Models for the Human Immunodeficiency Virus with Applications to Epitope Prediction and the Natural Selection of Escape Variants
(2012-02-08)In this thesis, evolutionary models are developed for protein coding sequences of the human immunodeficiency virus (HIV). These models are applied to predict the epitopes targeted by the cell-mediated and humoral arms of ... -
Evolving Racetrack Knowledge in a Racing Game.
(21st National Conference on Artificial Intelligence and Cognitive Science, 2010-07-30)This paper discusses the use of a Genetic Algorithm (GA) to evolve waypoint-based racing lines for computer-controlled cars in an online game. One goal is the reduction of developer effort, in order to automatically produce ... -
Ex vivo generation of bone marrow derived regulatory dendritic cells for promotion of corneal allograft survival.
(2013-09-27)Investigations into cell based therapies for application in organ transplantation has grown significantly. Here, I describe the ex vivo generation of donor bone marrow derived dendritic cells (BMDCs) and examine the ... -
Ex vivo investigation of iron handling in the brain
(2016-11-04)Aberrant iron deposition in the brain is associated with aging and neurodegenerative disorders including multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. It is unclear whether metabolic dyshomeostasis of ... -
Ex-vivo generation of regulatory T-cells expressing transcription factor foxp3 and their application in cornea transplantation
(2011-05-27)This project investigated the therapeutic potential of allo-antigen specific regulatory T-cells in the context of penetrating keratoplasty. Two methods of ex-vivo generation of T regulatory cells have been explored in ... -
Examination of Flood Estimation Techniques in the Irish Context
(2010-07-07)This thesis deals with the determination of the most suitable methods of finding the food magnitude-return period relationship for Irish flood data using the annual maximum statistical model. Data from approximately 200 ... -
An examination of gender differences in the impact of individual and organisational factors on work hours, work-life conflict and psychological strain in academics
(Routledge / Taylor & Francis, 2015-04-21)The current study used multi-group structural equation modelling (SEM) to test a fully and partially mediated Extended Rational Model of Work-Life Conflict and examine the impact of job involvement, workaholism, work ... -
An examination of glass beads from early medieval Ireland
(2013-08-18)This is the first dedicated and comprehensive study of glass beads from Early Medieval Ireland, presenting the first national classification, typology, dating and consideration of the social context and symbology of glass ... -
Examination of homogeneity of selected Irish pooling groups
(2010)In regional flood frequency estimation, a homogeneous pooling group of sites leads to a reduction in the error of quantile estimators which is the main aim of a regional flood frequency analysis. Examination of the homogeneity ... -
An Examination of Selected Psychophysiological Parameters of Stress in Parents of Children with Autism Spectrum Disorders
(2013-11-06)Autism Spectrum Disorders (ASD) are neurodevelopmental disorders that are often associated with a broad range of difficulties and challenges for the individual. Parents of children with ASD often experience higher levels ... -
An examination of the Auxiliary Division, Royal Irish Constabulary, exploring possible links between conduct and conflict-related injury, traumatic experiences and stress
(2017-05-12)The Auxiliary Division of the Royal Irish Constabulary (ADRIC) was a paramilitary adjutant, recruited from demobilised ex-officers, during the Anglo-Irish War 1920-1921. Although reputedly a ‘Corps d’Élite’, in reality ... -
An examination of the effects of argument mapping on students' memory and comprehension performance
(Elsevier, 2013-04)Argument mapping (AM) is a method of visually diagramming arguments to allow for easy comprehension of core statements and relations. A series of three experiments compared argument map reading and construction with ... -
Examination of the Impact of Emerging Technologies on eLearning
(Association for the Advancement of Computing in Education, 2007)eLearning has, to date, mostly been a matter of content being displayed on PCs running Windows, Linux, or MAC OS. Emerging technologies have recently, however, expanded the capabilities and scope of portable and mobile ... -
An examination of the interactions between the real and financial economy
(2015-10-15)The primary aim of this thesis is to critically examine the interactions between the real and financial economy, particularly in the context of financialisation, and its implications for the transmission of monetary policy. ... -
An examination of the Tree of Life and Tree of Knowledge In Irish Christian art and iconography
(2016-11-29)This thesis is the first study investigating the motif of the Tree of Life and Tree of Knowledge in Irish Christian art and iconography between the seventh and twelfth centuries AD. It deals with the pre-Christian Irish ... -
An examination of working hours, work-life conflict and psychological well-being in Irish academics.
(2013-09-02)Research from numerous countries across the world indicates that academics are experiencing high levels of occupational stress and trends indicate that stress levels are increasing over time. Two stressors which have been ... -
Examining a new class of dual CDC7/CDK9 inhibitors, mechanisms of proliferation, and proliferation-based stratification in myeloma
(2014-09-05)A key feature of progressive myeloma is a relative increase in proliferation. The DBF4-dependent kinase (DDK), cell division cycle 7 (CDC7), is an essential kinase for initiation of DNA replication. This thesis assesses ... -
Examining Customer Focus in Agile Systems Development Teams - Findings from Irish and Norwegian Case Studies
(2011)While an acute, continuous focus on customer needs is often cited as a key benefit of agile approaches, very little research has examined the customer focus construct in an agile project environment, or looked at the ... -
Examining the dynamical transition in the Dow Jones Industrial Index from Bull to Bear market using Recurrence Quantification Analysis
(2012-11-20)We present evidence of phase transitions (periodic to chaotic and chaotic to chaotic) in the Dow Jones Industrial Index as it transitions from Bull to Bear market. There is also evidence of a completely unpredictable (i.e., ...