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The effects of blood–brain barrier disruption on glial cell function in multiple sclerosis: figure 1
(Portland Press Ltd., 2009-02-01)
Dysfunction of the BBB (blood-brain barrier) is a major hallmark of MS (multiple sclerosis). Studies in our laboratories over the last decade have shown that increased 131313 permeability is associated with decreased ...
Therapeutic use of dolls for people living with dementia: a critical review of the literature
(SAGE Publications, 2014-08-25)
Background: There are a number of therapies currently available to assist healthcare professionals and carers with non-pharmacological treatment for people living with dementia. One such therapy that has been growing in ...
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
(Springer Nature, 2017-10-23)
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease(1). We conducted a GWAS using 21,468 ER-negative ...
Isolation of streptococcus agalactiae and an aquatic birnavirus from doctor fish garra rufa l
(Springer Nature, 2013-01-01)
Background: The doctor fish, Garra rufa, has become increasingly popular as a treatment for skin disorders and for pedicures in recent years. Despite this there is very little information available regarding the welfare ...
Genetic diversity and associated pathology of rhabdovirus infections in farmed and wild perch perca fluviatilis in ireland
(Inter-Research Science Center, 2014-12-02)
Rhabdovirus infections are an emerging problem for both wild and farmed freshwater fish in Northern Europe. In October 2005, a clinical outbreak with an approximate mortality rate of 40% occurred in a single batch of ...
Sternal metastasis - the forgotten column and its effect on thoracic spine stability
(Baishideng Publishing Group Inc., 2017-01-01)
Sternal metastases are not studied extensively in the literature. There is a paucity of information on their role in metastatic disease. The concept of the fourth column was described by Berg in 1993, and has been proven ...
Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
(Springer Nature, 2015-02-05)
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and, despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci identified to date are shared with ...
Resolution of a protracted serogroup b meningococcal outbreak with whole-genome sequencing shows interspecies genetic transfer
(American Society for Microbiology, 2016-09-14)
A carriage study was undertaken (n = 112) to ascertain the prevalence of Neisseria spp. following the eighth case of invasive meningococcal disease in young children (5 to 46 months) and members of a large extended indigenous ...
Multidimensional severity assessment in bronchiectasis: an analysis of seven european cohorts
(BMJ, 2016-08-11)
Introduction Bronchiectasis is a multidimensional disease associated with substantial morbidity and mortality. Two disease-specific clinical prediction tools have been developed, the Bronchiectasis Severity Index (BSI) and ...