Search
Now showing items 61-70 of 145
Evolution of a research field—a micro (rna) example
(PeerJ, 2015-03-17)
Background. Every new scientific field can be traced back to a single, seminal publication. Therefore, a bibliometric analysis can yield significant insights into the history and potential future of a research field. This ...
Cutting edge: il-7 regulates the peripheral pool of adult ror + lymphoid tissue inducer cells
(The American Association of Immunologists, 2009-07-27)
During fetal life, CD4(+)CD3(-) lymphoid tissue inducer (LTi) cells are required for lymph node and Peyer's patch development in mice. In adult animals, CD4(+) CD3(-) cells are found in low numbers in lymphoid organs. ...
Development of a cucumis sativus tilling platform for forward and reverse genetics
(Public Library of Science (PLoS), 2014-05-16)
Background: Cucumber (Cucumis sativus) belongs to the Cucurbitaceae family that includes more than 800 species. The cucumber genome has been recently sequenced and annotated. Transcriptomics and genome sequencing of many ...
Loss of sigb in listeria monocytogenes strains egd-e and 10403s confers hyperresistance to hydrogen peroxide in stationary phase under aerobic conditions
(American Society for Microbiology, 2016-05-20)
SigB is the main stress gene regulator in Listeria monocytogenes affecting the expression of more than 150 genes and thus contributing to multiple-stress resistance. Despite its clear role in most stresses, its role in ...
Migrastatin analogues inhibit canine mammary cancer cell migration and invasion
(Public Library of Science (PLoS), 2013-10-08)
Background: Cancer spread to other organs is the main cause of death of oncological patients. Migration of cancer cells from a primary tumour is the crucial step in the complex process of metastasis, therefore blocking ...
The major autolysin is redundant forstaphylococcus aureususa300 lac je2 virulence in a murine device-related infection model
(Oxford University Press (OUP), 2016-04-03)
The major Staphylococcus aureus autolysin, Atl, has been implicated in attachment to surfaces and release of extracellular DNA during biofilm formation under laboratory conditions. Consistent with this, polyclonal antibodies ...
Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia
(Springer Nature, 2009-09-30)
A three-marker C-A-T dysbindin haplotype identified by Williams et al (PMID: 15066891) is associated with increased risk for schizophrenia, decreased mRNA expression, poorer cognitive performance, and early sensory processing ...
Exploring circulating micro-rna in the neoadjuvant treatment of breast cancer
(Wiley-Blackwell, 2016-01-30)
Breast cancer is the most frequently diagnosed malignancy amongst females worldwide. In recent years the management of this disease has transformed considerably, including the administration of chemotherapy in the neoadjuvant ...
Differential impact of hormone receptor status on survival and recurrence for her2 receptor-positive breast cancers treated with trastuzumab
(Springer Nature, 2017-04-04)
Introduction Hormone receptor status has major implications for treatment and survival of breast cancer. Yet the impact of hormone receptor status on outcome after Trastuzumab has received little attention. The objective ...
Fibronectin-binding proteins are required for biofilm formation by community-associated methicillin-resistantstaphylococcus aureusstrain lac
(Oxford University Press (OUP), 2014-04-01)
Community-associated methicillin-resistant Staphylococcus aureus of the USA300 lineage is emerging as an important cause of medical device-related infection. However, few factors required for biofilm accumulation by USA300 ...