Now showing items 31-40 of 81
Oup accepted manuscript
(Oxford University Press (OUP), 2018-01-01)
Psychosocial adversity in childhood (e.g. abuse) and low socioeconomic position (SEP) can have significant lasting effects on social and health outcomes. DNA methylation-based biomarkers are highly correlated with chronological ...
Optimism and recovery after acute coronary syndrome
(Ovid Technologies (Wolters Kluwer Health), 2015-04-01)
Objective Optimism is associated with reduced cardiovascular mortality, but its impact on recovery after acute coronary syndrome (ACS) is poorly understood. We hypothesized that greater optimism would lead to more effective ...
Policy drivers of farm succession and inheritance
(Elsevier BV, 2017-02-01)
Impact of the choice of normalization method on molecular cancer class discovery using nonnegative matrix factorization
(Public Library of Science (PLoS), 2016-10-14)
Nonnegative Matrix Factorization (NMF) has proved to be an effective method for unsupervised clustering analysis of gene expression data. By the nonnegativity constraint, NMF provides a decomposition of the data matrix ...
Older adults, falls and technologies for independent living: a life space approach
(Cambridge University Press (CUP), 2011-05-16)
This paper draws attention to the need for further understanding of the fine details of routine and taken-for-granted daily activities and mobility. It argues that such understanding is critical if technologies designed ...
Psychological coping and recurrent major adverse cardiac events following acute coronary syndrome
(Royal College of Psychiatrists, 2015-05-07)
Background Depressed mood and stress are associated with recurrent adverse outcomes following acute coronary syndrome (ACS), but the impact of psychological coping style has not been evaluated in detail. Aims We tested the ...
A large-scale assessment of two-way snp interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium
(Oxford University Press (OUP), 2013-11-15)
Part of the substantial unexplained familial aggregation of breast cancer may be due to interactions between common variants, but few studies have had adequate statistical power to detect interactions of realistic magnitude. ...
Investigating the association of rs2910164 with cancer in irish patients
Introduction: MicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA). Polymorphisms in genes ...
Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
(American Association for Cancer Research (AACR), 2011-07-27)