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Symmetry difference electrical impedance tomography - a novel modality for anomaly detection
(IOP Publishing, 2018-03-13)
Objective: The theoretical basis, experimental implementation, and proof of concept of a novel electrical impedance tomography (EIT) imaging technique, called symmetry difference EIT, is described. This technique is ...
Biopolymer-based nanoparticles for cystic fibrosis lung gene therapy studies
(MDPI AG, 2018-01-13)
Lung gene therapy for cystic fibrosis disease has not been successful due to several challenges such as the absence of an appropriate vector. Therefore, optimal delivery of emerging therapeutics to airway epithelial cells ...
Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options
(Springer Nature, 2018-02-20)
Background: Recent studies have shown that breast cancer subtype can change from the primary tumour to the recurrence. Discordance between primary and recurrent breast cancer has implications for further treatment and ...
Establishment of the european meningococcal strain collection genome library (emsc-gl) for the 2011 to 2012 epidemiological year
(European Centre for Disease Control and Prevention (ECDC), 2018-05-17)
Invasive meningococcal disease surveillance in Europe combines isolate characterisation and epidemiological data to support public health intervention. A representative European Meningococcal Strain Collection (EMSC) of ...
Vspipe, an integrated resource for virtual screening and hit selection: applications to protein tyrosine phospahatase inhibition
(MDPI AG, 2018-02-07)
The use of computational tools for virtual screening provides a cost-efficient approach to select starting points for drug development. We have developed VSpipe, a user-friendly semi-automated pipeline for structure-based ...