Now showing items 1-6 of 6
Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
(Springer Nature, 2015-02-05)
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and, despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci identified to date are shared with ...
Long-term costs of introducing hpv-dna post-treatment surveillance to national cervical cancer screening in ireland
(Informa UK Limited, 2015-09-17)
Introduction: Co-testing (cytology plus human papillomavirus DNA testing) as part of cervical cancer surveillance in Ireland increases one-time testing costs. Of interest to policy makers was the long-term impact of these ...
Development of a rapid recombinase polymerase amplification assay for the detection of streptococcus pneumoniae in whole blood
(Springer Nature, 2015-10-29)
Background: Streptococcus pneumoniae is an important cause of microbial disease in humans. The introduction of multivalent vaccines has coincided with a dramatic decrease in the number of pneumococcal-related deaths. In ...
Stabilization of metastatic lesions affecting the second cervical vertebra
Purpose: Metastatic spine disease is an ever-increasing burden on health care systems. Certain levels in the spine confer unique biomechanical characteristics and hence are of interest. Isolated C2 lesions are rare. We ...
Surgical management of metastatic lesions at the cervicothoracic junction
Purpose: The cervicothoracic junction (CTJ) represents a transition from the semirigid thoracic spine to the mobile subaxial cervical spine. Pathologic lesions are prone to kyphotic deformity. The aim of this study was to ...
The digital revolution in phenotyping
(Oxford University Press (OUP), 2015-09-29)
Phenotypes have gained increased notoriety in the clinical and biological domain owing to their application in numerous areas such as the discovery of disease genes and drug targets, phylogenetics and pharmacogenomics. ...