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Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under er stress conditions
(Informa UK Limited, 2014-11-02)
Endoplasmic reticulum (ER) stress-induced cell death is normally associated with activation of the mitochondrial apoptotic pathway, which is characterized by CYCS (cytochrome c, somatic) release, apoptosome formation, and ...
Mirna signature of unfolded protein response in h9c2 rat cardiomyoblasts
(Springer Nature, 2014-01-01)
Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling ...