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The pyrrolo-1,5-benzoxazepine, pbox-15, enhances trail-induced apoptosis by upregulation of dr5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells
(Spandidos Publications, 2016-05-11)
Apoptotic defects are frequently associated with poor outcome in pediatric acute lymphoblastic leukaemia (ALL) hence there is an ongoing demand for novel strategies that counteract apoptotic resistance. The death ligand ...
Eradication of staphylococcus aureus catheter-related biofilm infections using ml:8 and citrox
(American Society for Microbiology, 2016-07-25)
Staphylococci are a leading cause of catheter-related infections (CRIs) due to biofilm formation. CRIs are typically managed by either device removal or systemic antibiotics, often in combination with catheter lock solutions ...