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5-hydroxyethyl-3-tetradecanoyltetramic acid represents a novel treatment for intravascular catheter infections due tostaphylococcus aureus

Zapotoczna, Marta; Murray, Ewan J.; Hogan, Siobhan; O’Gara, James P.; Chhabra, Siri R.; Chan, Weng C.; O’Neill, Eoghan; Williams, Paul (Oxford University Press (OUP), 2016-12-20)

Objectives: Biofilm infections of intravascular catheters caused by Staphylococcus aureus may be treated with catheter lock solutions (CLSs). Here we investigated the antibacterial activity, cytotoxicity and CLS potential ...

Eradication of staphylococcus aureus catheter-related biofilm infections using ml:8 and citrox

Hogan, S.; Zapotoczna, M.; Stevens, N. T.; Humphreys, H.; O'Gara, J. P.; O'Neill, E. (American Society for Microbiology, 2016-07-25)

Staphylococci are a leading cause of catheter-related infections (CRIs) due to biofilm formation. CRIs are typically managed by either device removal or systemic antibiotics, often in combination with catheter lock solutions ...