Search
Now showing items 1-3 of 3
Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in listeria monocytogenes egd-e and 10403s: roles in virulence and acid tolerance
(Public Library of Science (PLoS), 2014-11-11)
The glutamate decarboxylase (GAD) system has been shown to be important for the survival of Listeria monocytogenes in low pH environments. The bacterium can use this faculty to maintain pH homeostasis under acidic conditions. ...
Co-acting gene networks predict trail responsiveness of tumour cells with high accuracy
(Springer Nature, 2014-01-01)
Background: Identification of differentially expressed genes from transcriptomic studies is one of the most common mechanisms to identify tumor biomarkers. This approach however is not well suited to identify interaction ...
Tumor microenvironment-based feed-forward regulation of nos2 in breast cancer progression
(Proceedings of the National Academy of Sciences, 2014-04-14)
Inflammation is widely recognized as an inducer of cancer progression. The inflammation-associated enzyme, inducible nitric oxide synthase (NOS2), has emerged as a candidate oncogene in estrogen receptor (ER)-negative ...